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8OT4	seeded Abeta(1-40) amyloid fibril (morphology I) Descriptor: Amyloid-beta A4 protein Authors: Pfeiffer, P.B, Schmidt, M, Faendrich, M. Deposit date: 2023-04-20 Release date: 2024-02-07 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Cryo-EM Analysis of the Effect of Seeding with Brain-derived A beta Amyloid Fibrils. J.Mol.Biol., 436, 2023
8OWJ	Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2 Descriptor: Amyloid-beta A4 protein Authors: Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. Deposit date: 2023-04-28 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
8OVM	Lipidic amyloid-beta(1-40) fibril - polymorph L2 Descriptor: Amyloid-beta A4 protein Authors: Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. Deposit date: 2023-04-26 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
8OWE	Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3 Descriptor: Amyloid-beta A4 protein Authors: Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. Deposit date: 2023-04-27 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
8OVK	Lipidic amyloid-beta(1-40) fibril - polymorph L1 Descriptor: Amyloid-beta A4 protein Authors: Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. Deposit date: 2023-04-26 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (2.88 Å) Cite: Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
8OWK	Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3 Descriptor: Amyloid-beta A4 protein Authors: Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. Deposit date: 2023-04-28 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
8OWD	Lipidic amyloid-beta(1-40) fibril - polymorph L3 Descriptor: Amyloid-beta A4 protein Authors: Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. Deposit date: 2023-04-27 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
8QN7	Amyloid-beta 40 type 1 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy Descriptor: Amyloid-beta A4 protein Authors: Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W. Deposit date: 2023-09-25 Release date: 2023-12-13 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy. Acta Neuropathol Commun, 11, 2023
8QN6	Amyloid-beta 40 type 2 filament from the leptomeninges of individual with Alzheimer's disease and cerebral amyloid angiopathy Descriptor: Amyloid-beta A4 protein Authors: Yang, Y, Murzin, A.S, Peak-Chew, S.Y, Franco, C, Newell, K.L, Ghetti, B, Goedert, M, Scheres, S.H.W. Deposit date: 2023-09-25 Release date: 2023-12-13 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Cryo-EM structures of A beta 40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy. Acta Neuropathol Commun, 11, 2023
8SEJ	Type I beta-amyloid 42 Filaments from Down syndrome Descriptor: Amyloid-beta protein 42 Authors: Hoq, M.R, Bharath, S.R, Vago, F.S, Jiang, W. Deposit date: 2023-04-10 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 2024
8SEK	Type IIIa beta-amyloid 40 Filaments from Down syndrome Descriptor: Type IIIb beta-amyloid 40 Filament Authors: Hoq, M.R, Vago, F.S, Bharath, S.R, Jiang, W. Deposit date: 2023-04-10 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 2024
8SEL	Type IIIb beta-amyloid 40 Filaments from Down Syndrome Descriptor: Amyloid-beta protein 40 Authors: Hoq, M.R, Vago, F.S, Bharath, S.R, Jiang, W. Deposit date: 2023-04-10 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 2024
2LMO	Structural Model for a 40-Residue Beta-Amyloid Fibril with Two-Fold Symmetry, Negative Stagger Descriptor: Beta-amyloid protein 40 Authors: Tycko, R, Petkova, A. Deposit date: 2011-12-08 Release date: 2011-12-28 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2LNQ	40-residue D23N beta amyloid fibril Descriptor: P3(40) Authors: Qiang, W, Yau, W, Luo, Y, Mattson, M.P, Tycko, R. Deposit date: 2012-01-03 Release date: 2012-02-08 Last modified: 2023-06-14 Method: SOLID-STATE NMR Cite: Antiparallel beta-sheet architecture in Iowa-mutant beta-amyloid fibrils. Proc.Natl.Acad.Sci.USA, 109, 2012
2LOH	Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment Descriptor: P3(42) Authors: Nadezhdin, K, Bocharov, E, Bocharova, O, Arseniev, A. Deposit date: 2012-01-24 Release date: 2012-05-23 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment. Febs Lett., 586, 2012
2LFM	A partially folded structure of amyloid-beta(1 40) in an aqueous environment Descriptor: Beta-amyloid protein 40 Authors: Vivekanandan, S, Brender, J.R, Lee, S.Y, Ramamoorthy, A. Deposit date: 2011-07-06 Release date: 2011-07-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A partially folded structure of amyloid-beta(1-40) in an aqueous environment. Biochem.Biophys.Res.Commun., 411, 2011
2LMQ	Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Negative Stagger Descriptor: Beta-amyloid protein 40 Authors: Tycko, R, Paravastu, A. Deposit date: 2011-12-09 Release date: 2011-12-28 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proc. Natl. Acad. Sci. U.S.A., 105, 2008
2MJ1	NMR structure of the soluble A beta 17-34 peptide Descriptor: Amyloid beta A4 protein Authors: Fonar, G, Samson, A.O. Deposit date: 2013-12-23 Release date: 2014-11-05 Last modified: 2022-08-24 Method: SOLUTION NMR Cite: NMR structure of the water soluble A beta 17-34 peptide. Biosci.Rep., 34, 2014
2LZ3	Solution NMR structure of transmembrane domain of amyloid precursor protein WT Descriptor: Amyloid beta A4 protein Authors: Chen, W, Wang, C. Deposit date: 2012-09-23 Release date: 2013-10-02 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5, 2014
2LZ4	Solution NMR structure of transmembrane domain of amyloid precursor protein V44M Descriptor: Amyloid beta A4 protein Authors: Chen, W, Wang, C. Deposit date: 2012-09-23 Release date: 2013-10-02 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5, 2014
2M4J	40-residue beta-amyloid fibril derived from Alzheimer's disease brain Descriptor: Amyloid beta A4 protein Authors: Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R. Deposit date: 2013-02-05 Release date: 2013-09-25 Last modified: 2023-06-14 Method: SOLID-STATE NMR Cite: Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue. Cell(Cambridge,Mass.), 154, 2013
2MXU	42-Residue Beta Amyloid Fibril Descriptor: Amyloid beta A4 protein Authors: Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y. Deposit date: 2015-01-14 Release date: 2015-05-06 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Nat.Struct.Mol.Biol., 22, 2015
2OTK	Structure of Alzheimer Ab peptide in complex with an engineered binding protein Descriptor: Amyloid beta A4 protein, ZAb3 Affibody dimer Authors: Hoyer, W, Hard, T. Deposit date: 2007-02-08 Release date: 2008-02-12 Last modified: 2019-12-04 Method: SOLUTION NMR Cite: Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation. Proc.Natl.Acad.Sci.Usa, 105, 2008
2NAO	Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibril Descriptor: Beta-amyloid protein 42 Authors: Waelti, M.A, Ravotti, F, Arai, H, Glabe, C, Wall, J, Bockmann, A, Guntert, P, Meier, B.H, Riek, R. Deposit date: 2016-01-07 Release date: 2016-07-27 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Atomic-resolution structure of a disease-relevant A beta (1-42) amyloid fibril. Proc.Natl.Acad.Sci.USA, 113, 2016
2MVX	Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutation Descriptor: Amyloid beta A4 protein Authors: Schuetz, A.K, Vagt, T, Huber, M, Ovchinnikova, O.Y, Cadalbert, R, Wall, J, Guentert, P, Bockmann, A, Glockshuber, R, Meier, B.H. Deposit date: 2014-10-17 Release date: 2014-11-26 Last modified: 2024-05-01 Method: SOLID-STATE NMR Cite: Atomic-Resolution Three-Dimensional Structure of Amyloid beta Fibrils Bearing the Osaka Mutation. Angew.Chem.Int.Ed.Engl., 54, 2015

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