2OTK
Structure of Alzheimer Ab peptide in complex with an engineered binding protein
Summary for 2OTK
Entry DOI | 10.2210/pdb2otk/pdb |
Descriptor | Amyloid beta A4 protein, ZAb3 Affibody dimer (2 entities in total) |
Functional Keywords | protein-peptide complex, beta-hairpin, intermolecular beta-sheet, de novo protein, peptide binding protein |
Biological source | engineered binding protein More |
Total number of polymer chains | 3 |
Total formula weight | 19967.09 |
Authors | |
Primary citation | Hoyer, W.,Gronwall, C.,Jonsson, A.,Stahl, S.,Hard, T. Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation. Proc.Natl.Acad.Sci.Usa, 105:5099-5104, 2008 Cited by PubMed: 18375754DOI: 10.1073/pnas.0711731105 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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