PDB: 467 件ウェブページステータス検索Chemie searchBIRD

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4OLZ	Crystal structure of antibody VRC07-G54W in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLV	Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLY	Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OM0	Crystal structure of antibody VRC07-G54Y in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.289 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLW	Crystal structure of antibody VRC07-G54H in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.709 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLX	Crystal structure of antibody VRC07-G54L in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4R4N	Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... 著者 Acharya, P, Louder, R, Kwong, P.D. 登録日 2014-08-19 公開日 2014-11-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
4RFO	Crystal structure of the ADCC-Potent Antibody N60-I3 Fab in complex with HIV-1 Clade A/E gp120 and M48u1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade A/E gp120, N60-i3 Fab heavy chain, ... 著者 Tolbert, W.D, Gohain, N, Pazgier, M. 登録日 2014-09-26 公開日 2015-07-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
4R4F	Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120 分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, ... 著者 Acharya, P, Kwong, P.D. 登録日 2014-08-19 公開日 2014-09-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.514 Å) 主引用文献 Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
4RFN	Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, ... 著者 Gohain, N, Tolbert, W.D, Pazgier, M. 登録日 2014-09-26 公開日 2015-07-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
4RZ8	Crystal structure of HIV-1 gp120 core in complex with NBD-11021, a small molecule CD4-antagonist 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-(4-chlorophenyl)-N-{(S)-[5-(hydroxymethyl)-4-methyl-1,3-thiazol-2-yl][(2R)-piperidin-2-yl]methyl}-1H-pyrrole-2-carboxamide, ... 著者 Kwon, Y.D, Debnath, A.K, Kwong, P.D. 登録日 2014-12-18 公開日 2015-09-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity. J.Med.Chem., 58, 2015
4S1R	Crystal structure of a VRC01-lineage antibody, 45-VRC01.H08.F-117225, in complex with clade A/E HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of VRC01 light chain, Fab of VRC01-lineage antibody,45-VRC01.H08.F-117225 heavy chain, ... 著者 Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D. 登録日 2015-01-14 公開日 2015-04-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.214 Å) 主引用文献 Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell(Cambridge,Mass.), 161, 2015
4S1Q	Crystal structure of a VRC01-lineage antibody, 45-VRC01.H03+06.D-001739, in complex with clade A/E HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of VRC01 light chain, Fab of VRC01-lineage antibody,45-VRC01.H03+06.D-001739 heavy chain, ... 著者 Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D. 登録日 2015-01-14 公開日 2015-04-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell(Cambridge,Mass.), 161, 2015
4RX4	Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ... 著者 Zhou, T, Acharya, P, Moquin, S, Kwong, P.D. 登録日 2014-12-08 公開日 2015-07-01 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell(Cambridge,Mass.), 161, 2015
4S1S	Crystal structure of a VRC01-lineage antibody, 45-VRC01.H5.F-185917, in complex with clade A/E HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab of VRC01 light chain, ... 著者 Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D. 登録日 2015-01-14 公開日 2015-04-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.39 Å) 主引用文献 Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell(Cambridge,Mass.), 161, 2015
4RWY	Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Acharya, P, Luongo, T.S, Kwong, P.D. 登録日 2014-12-08 公開日 2015-07-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.128 Å) 主引用文献 Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell(Cambridge,Mass.), 161, 2015
8SAU	CryoEM structure of DH270.4-CH848.10.17 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... 著者 Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. 登録日 2023-04-02 公開日 2023-04-19 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
8SB4	CryoEM structure of DH270.1-CH848.10.17 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... 著者 Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. 登録日 2023-04-02 公開日 2023-04-19 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
8SAZ	CryoEM structure of DH270.I5.6-CH848.10.17 分子名称: CH848.10.17.SOSIP gp41, DH270.I5.6 variable heavy chain, DH270.I5.6 variable light chain, ... 著者 Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. 登録日 2023-04-02 公開日 2023-04-19 最終更新日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
8SXJ	CH505 Disulfide Stapled SOSIP Bound to CH235.12 Fab 分子名称: CH235.12 Heavy Chain, CH235.12 Light Chain, Envelope glycoprotein gp160, ... 著者 Henderson, R. 登録日 2023-05-22 公開日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv, 10, 2024
7RI1	Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Lamma VHH antibody J3, ... 著者 Zhou, T, Kwong, P.D. 登録日 2021-07-19 公開日 2022-03-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7RI2	Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, anti-HIV llama VHH antibody A12 著者 Zhou, T, Kwong, P.D. 登録日 2021-07-19 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7R73	Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Llama antibody D7 著者 Zhou, T, Kwong, P.D. 登録日 2021-06-24 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7R74	Crystal structure of llama VHH antibody in complex with HIV-1 HXBC2 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C8 VHH domain, Glycoprotein 120 著者 Zhou, T, Kwong, P.D. 登録日 2021-06-24 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7RDW	Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... 著者 Weidle, C, Pancera, M. 登録日 2021-07-12 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain. Sci Adv, 8, 2022

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