PDB: 153 件ウェブページステータス検索Chemie searchBIRD

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6IIL	USP14 catalytic domain bind to IU1-47 分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, Y.W, Wang, F, Wang, J.W, He, W, Ding, S, Li, J.W. 登録日 2018-10-07 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
6H4J	Usp25 catalytic domain 分子名称: CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 25 著者 Klemm, T.A, Sauer, F, Kisker, C. 登録日 2018-07-21 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Mol.Cell, 74, 2019
6H4I	Usp28 catalytic domain apo 分子名称: SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 28 著者 Klemm, T.A, Sauer, F, Kisker, C. 登録日 2018-07-21 公開日 2019-03-27 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Mol.Cell, 74, 2019
7TUO	Crystal structure analysis of human USP28 complex with a compound 分子名称: 7-amino-N-(2-{4-[(1R,3s,5S)-8-azabicyclo[3.2.1]octan-3-yl]phenyl}ethyl)-3-methylthieno[2,3-b]pyrazine-6-carboxamide, CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase 28 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2022-02-03 公開日 2023-02-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal Structure Analysis of human USP28 complex with a compound To Be Published
7W3R	USP34 catalytic domain 分子名称: Ubiquitin carboxyl-terminal hydrolase 34, ZINC ION 著者 Xu, G.L, Ming, Z.H. 登録日 2021-11-26 公開日 2022-06-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural Insights into the Catalytic Mechanism and Ubiquitin Recognition of USP34. J.Mol.Biol., 434, 2022
4W4U	Structure of yeast SAGA DUBm with Sgf73 Y57A mutant at 2.8 angstroms resolution 分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ... 著者 Wolberger, C, Yan, M. 登録日 2014-08-15 公開日 2015-07-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity. J.Mol.Biol., 427, 2015
4WA6	Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution 分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ... 著者 Wolberger, C, Yan, M. 登録日 2014-08-28 公開日 2015-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution To Be Published
2F1Z	Crystal structure of HAUSP 分子名称: Ubiquitin carboxyl-terminal hydrolase 7 著者 Hu, M, Gu, L, Jeffrey, P.D, Shi, Y. 登録日 2005-11-15 公開日 2006-02-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway. Plos Biol., 4, 2006
5FWI	structure of usp7 catalytic domain and three ubl-domains 分子名称: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 著者 Kim, R.Q, van Dijk, W.J, Sixma, T.K. 登録日 2016-02-17 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of Usp7 Catalytic Domain and Three Ubl-Domains Reveals a Connector Alpha-Helix with Regulatory Role. J.Struct.Biol., 195, 2016
4FIP	Structure of the SAGA Ubp8(S144N)/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module 分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Samara, N.L, Ringel, A.E, Wolberger, C. 登録日 2012-06-10 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.686 Å) 主引用文献 A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
4FK5	Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... 著者 Samara, N.L, Ringel, A.E, Wolberger, C. 登録日 2012-06-12 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.032 Å) 主引用文献 A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
4FJC	Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module 分子名称: GLYCEROL, Protein SUS1, SAGA-associated factor 11, ... 著者 Samara, N.L, Ringel, A.E, Wolberger, C. 登録日 2012-06-11 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.826 Å) 主引用文献 A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
4MSX	Crystal structure of an essential yeast splicing factor 分子名称: ACETATE ION, Pre-mRNA-splicing factor SAD1, ZINC ION 著者 Hadjivassiliou, H, Guthrie, C, Rosenberg, O.S. 登録日 2013-09-18 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. Rna, 20, 2014
3M99	Structure of the Ubp8-Sgf11-Sgf73-Sus1 SAGA DUB module 分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Kohler, A, Zimmerman, E, Schneider, M, Hurt, E, Zheng, N. 登録日 2010-03-21 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module. Cell(Cambridge,Mass.), 141, 2010
5J7T	Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation 分子名称: Ubiquitin carboxyl-terminal hydrolase 7 著者 Murray, J.M, Rouge, L. 登録日 2016-04-06 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2001 Å) 主引用文献 Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation. Structure, 24, 2016
3MHH	Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module 分子名称: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... 著者 Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. 登録日 2010-04-08 公開日 2010-04-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
5O71	Crystal structure of human USP25 分子名称: Ubiquitin carboxyl-terminal hydrolase 25 著者 Reverter, D, Liu, B. 登録日 2017-06-07 公開日 2018-06-20 最終更新日 2019-04-17 実験手法 X-RAY DIFFRACTION (3.283 Å) 主引用文献 A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25. Nat Commun, 9, 2018
7YXX	Cryo-EM structure of USP9X 分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X 著者 Deme, J.C, Halabelian, L, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) 登録日 2022-02-16 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of USP9X To Be Published
7YXY	Cryo-EM structure of USP9X, local refinement of monomer 分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X 著者 Deme, J.C, Halabelian, L, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) 登録日 2022-02-16 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structure of USP9X To Be Published
5K1B	Crystal structure of the UAF1/USP12 complex in F222 space group 分子名称: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION 著者 Li, H, D'Andrea, A.D, Zheng, N. 登録日 2016-05-18 公開日 2016-07-20 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63, 2016
8OYP	Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic 分子名称: CADMIUM ION, CHLORIDE ION, GLYCEROL, ... 著者 Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299, 2023
5CVN	WDR48 (2-580):USP46~ubiquitin ternary complex 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ... 著者 Harris, S.F, Yin, J. 登録日 2015-07-27 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
6DGF	Ubiquitin Variant bound to USP2 分子名称: Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 2, ... 著者 Manczyk, N, Sicheri, F. 登録日 2018-05-17 公開日 2019-02-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases. J. Mol. Biol., 431, 2019
2Y5B	Structure of USP21 in complex with linear diubiquitin-aldehyde 分子名称: SULFATE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21, ... 著者 Ye, Y, Akutsu, M, Reyes-Turcu, F, Enchev, R.I, Wilkinson, K.D, Komander, D. 登録日 2011-01-12 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Polyubiquitin Binding and Cross-Reactivity in the Usp Domain Deubiquitinase Usp21. Embo Rep., 12, 2011
1NBF	Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde 分子名称: Ubiquitin aldehyde, Ubiquitin carboxyl-terminal hydrolase 7 著者 Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y. 登録日 2002-12-02 公開日 2003-01-07 最終更新日 2018-10-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde Cell(Cambridge,Mass.), 111, 2002

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