7YXX
 
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7YXY
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6H3I
 | | Structural snapshots of the Type 9 protein translocon | | Descriptor: | Peptidyl-prolyl cis-trans isomerase, PorV, Protein involved in gliding motility SprA | | Authors: | Deme, J.C, Lea, S.M. | | Deposit date: | 2018-07-18 | | Release date: | 2018-11-07 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Type 9 secretion system structures reveal a new protein transport mechanism.
Nature, 564, 2018
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6H3J
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8UCS
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7OXR
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7OXP
 | | Cryo-EM structure of yeast Sei1 | | Descriptor: | BJ4_G0032880.mRNA.1.CDS.1,BJ4_G0032880.mRNA.1.CDS.1 | | Authors: | Deme, J.C, Lea, S.M. | | Deposit date: | 2021-06-22 | | Release date: | 2021-10-13 | | Last modified: | 2021-10-20 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex.
Nat Commun, 12, 2021
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8GL6
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8GLJ
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8GLK
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8GLN
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8GLM
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8GL8
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7AKV
 | | The cryo-EM structure of the Vag8-C1 inhibitor complex | | Descriptor: | Plasma protease C1 inhibitor, Vag8 | | Authors: | Johnson, S, Lea, S.M, Deme, J.C, Furlong, E, Dhillon, A. | | Deposit date: | 2020-10-02 | | Release date: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex.
Mbio, 12, 2021
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7BC6
 | | Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 | | Descriptor: | Proton-coupled folate transporter, nanobody | | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | Deposit date: | 2020-12-18 | | Release date: | 2021-05-12 | | Last modified: | 2021-08-11 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of antifolate recognition and transport by PCFT.
Nature, 595, 2021
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7BC7
 | | Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed | | Descriptor: | 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Proton-coupled folate transporter, nanobody | | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | Deposit date: | 2020-12-18 | | Release date: | 2021-05-12 | | Last modified: | 2021-08-11 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of antifolate recognition and transport by PCFT.
Nature, 595, 2021
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6TRE
 | | Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 32-fold symmetry applied | | Descriptor: | Flagellar M-ring protein | | Authors: | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | | Deposit date: | 2019-12-18 | | Release date: | 2020-03-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the bacterial flagellar rotor MS-ring: a minimum inventory/maximum diversity system.
To Be Published
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8UOX
 | | Cryo-EM structure of a Counterclockwise locked form of the Salmonella enterica Typhimurium flagellar C-ring, with C34 symmetry applied | | Descriptor: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | | Authors: | Johnson, S, Deme, J.C, Lea, S.M. | | Deposit date: | 2023-10-20 | | Release date: | 2024-01-24 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural basis of directional switching by the bacterial flagellum.
Nat Microbiol, 2024
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8UMD
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8UMX
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8FY3
 | | Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex | | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E. | | Deposit date: | 2023-01-25 | | Release date: | 2023-07-26 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
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8FY4
 | | Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex | | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E. | | Deposit date: | 2023-01-25 | | Release date: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
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7P9V
 | | Cryo EM structure of System XC- | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter | | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | Deposit date: | 2021-07-28 | | Release date: | 2021-11-17 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Molecular basis for redox control by the human cystine/glutamate antiporter system xc .
Nat Commun, 12, 2021
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7P9U
 | | Cryo EM structure of System XC- in complex with glutamate | | Descriptor: | 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter, GLUTAMIC ACID | | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | Deposit date: | 2021-07-28 | | Release date: | 2021-11-17 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular basis for redox control by the human cystine/glutamate antiporter system xc .
Nat Commun, 12, 2021
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6R6B
 | | Structure of the core Shigella flexneri type III secretion system export gate complex SctRST (Spa24/Spa9/Spa29). | | Descriptor: | Surface presentation of antigens protein SpaP, Surface presentation of antigens protein SpaQ, Surface presentation of antigens protein SpaR | | Authors: | Johnson, S, Kuhlen, L, Deme, J.C, Abrusci, P, Lea, S.M. | | Deposit date: | 2019-03-26 | | Release date: | 2019-05-29 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems.
Mbio, 10, 2019
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