7P9U

Cryo EM structure of System XC- in complex with glutamate

Summary for 7P9U

Entry DOI	10.2210/pdb7p9u/pdb
EMDB information	13266
Descriptor	4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter, GLUTAMIC ACID (3 entities in total)
Functional Keywords	transporter glutamate cystine, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	125775.60
Authors	Parker, J.L.,Deme, J.C.,Lea, S.M.,Newstead, S. (deposition date: 2021-07-28, release date: 2021-11-17, Last modification date: 2022-02-02)
Primary citation	Parker, J.L.,Deme, J.C.,Kolokouris, D.,Kuteyi, G.,Biggin, P.C.,Lea, S.M.,Newstead, S. Molecular basis for redox control by the human cystine/glutamate antiporter system xc . Nat Commun, 12:7147-7147, 2021 Cited by PubMed: 34880232 DOI: 10.1038/s41467-021-27414-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation