3NEJ
 
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3BOR
 | | Crystal structure of the DEADc domain of human translation initiation factor 4A-2 | | Descriptor: | Human initiation factor 4A-II | | Authors: | Dimov, S, Hong, B, Tempel, W, MacKenzie, F, Karlberg, T, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
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3P4Y
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3P4X
 | | Helicase domain of reverse gyrase from Thermotoga maritima | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-10-07 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | The Conformational Flexibility of the Helicase-like Domain from Thermotoga maritima Reverse Gyrase Is Restricted by the Topoisomerase Domain.
Biochemistry, 50, 2011
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3OIY
 | | Helicase domain of reverse gyrase from Thermotoga maritima | | Descriptor: | CHLORIDE ION, PYROPHOSPHATE 2-, reverse gyrase helicase domain | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-08-20 | | Release date: | 2010-12-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The latch modulates nucleotide and DNA binding to the helicase-like domain of Thermotoga maritima reverse gyrase and is required for positive DNA supercoiling.
Nucleic Acids Res., 39, 2011
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3DKP
 | | Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Lehtio, L, Karlberg, T, Andersson, J, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, van den Berg, S, Welin, M, Wisniewska, M, Wikstrom, M, Schueler, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-06-25 | | Release date: | 2008-08-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
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4PX9
 | | DEAD-box RNA helicase DDX3X Domain 1 with N-terminal ATP-binding Loop | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX3X | | Authors: | Epling, L.B, Grace, C.R, Lowe, B.R, Partridge, J.F, Enemark, E.J. | | Deposit date: | 2014-03-22 | | Release date: | 2015-03-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis.
J.Mol.Biol., 427, 2015
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3FHC
 | | Crystal structure of human Dbp5 in complex with Nup214 | | Descriptor: | ATP-dependent RNA helicase DDX19B, Nuclear pore complex protein Nup214 | | Authors: | von Moeller, H, Conti, E. | | Deposit date: | 2008-12-09 | | Release date: | 2009-02-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
Nat.Struct.Mol.Biol., 16, 2009
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3FE2
 | | Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX5, ... | | Authors: | Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-11-27 | | Release date: | 2008-12-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases
Plos One, 5, 2010
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3FMO
 | | Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, GLYCEROL, ... | | Authors: | Napetschnig, J, Debler, E.W, Blobel, G, Hoelz, A. | | Deposit date: | 2008-12-22 | | Release date: | 2009-05-19 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4A4D
 | | Crystal structure of the N-terminal domain of the Human DEAD-BOX RNA helicase DDX5 (P68) | | Descriptor: | PROBABLE ATP-DEPENDENT RNA HELICASE DDX5 | | Authors: | Dutta, S, Choi, Y.W, Kotaka, M, Fielding, B.C, Tan, Y.J. | | Deposit date: | 2011-10-11 | | Release date: | 2012-08-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Variable N-Terminal Region of Ddx5 Contains Structural Elements and Auto-Inhibits its Interaction with Ns5B of Hepatitis C Virus.
Biochem.J., 446, 2012
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3IUY
 | | Crystal structure of DDX53 DEAD-box domain | | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX53 | | Authors: | Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-08-31 | | Release date: | 2009-10-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
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7DTK
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8PNK
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5ZBZ
 | | Crystal structure of the DEAD domain of Human eIF4A with sanguinarine | | Descriptor: | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Eukaryotic initiation factor 4A-I, MALONATE ION | | Authors: | Ding, Y, Ding, L. | | Deposit date: | 2018-02-14 | | Release date: | 2019-02-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.30860257 Å) | | Cite: | Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling.
Cell Chem Biol, 26, 2019
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6AIB
 | | Crystal structures of the N-terminal RecA-like domain 1 of Staphylococcus aureus DEAD-box Cold shock RNA helicase CshA | | Descriptor: | DEAD-box ATP-dependent RNA helicase CshA | | Authors: | Chengliang, W, Tian, T, Xiaobao, C, Xuan, Z, Jianye, Z. | | Deposit date: | 2018-08-22 | | Release date: | 2018-11-21 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structures of the N-terminal domain of the Staphylococcus aureus DEAD-box RNA helicase CshA and its complex with AMP
Acta Crystallogr F Struct Biol Commun, 74, 2018
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6AIC
 | | Crystal structures of the N-terminal domain of Staphylococcus aureus DEAD-box Cold shock RNA helicase CshA in complex with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, DEAD-box ATP-dependent RNA helicase CshA | | Authors: | Tian, T, Chengliang, W, Xiaobao, C, Xuan, Z, Jianye, Z. | | Deposit date: | 2018-08-22 | | Release date: | 2018-11-21 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of the N-terminal domain of the Staphylococcus aureus DEAD-box RNA helicase CshA and its complex with AMP
Acta Crystallogr F Struct Biol Commun, 74, 2018
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4W7S
 | | Crystal structure of the yeast DEAD-box splicing factor Prp28 at 2.54 Angstroms resolution | | Descriptor: | GLYCEROL, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | | Authors: | Jacewicz, A, Smith, P, Schwer, B, Shuman, S. | | Deposit date: | 2014-08-22 | | Release date: | 2014-10-29 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.542 Å) | | Cite: | Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28.
Nucleic Acids Res., 42, 2014
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4XGT
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1OYW
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1OYY
 | | Structure of the RecQ Catalytic Core bound to ATP-gamma-S | | Descriptor: | ATP-dependent DNA helicase, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Bernstein, D.A, Zittel, M.C, Keck, J.L. | | Deposit date: | 2003-04-07 | | Release date: | 2003-10-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | High-resolution structure of the E. coli RecQ helicase catalytic core
Embo J., 22, 2003
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1WP9
 | | Crystal structure of Pyrococcus furiosus Hef helicase domain | | Descriptor: | ATP-dependent RNA helicase, putative, PHOSPHATE ION | | Authors: | Nishino, T, Komori, K, Tsuchiya, D, Ishino, Y, Morikawa, K. | | Deposit date: | 2004-08-31 | | Release date: | 2005-02-01 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure and Functional Implications of Pyrococcus furiosus Hef Helicase Domain Involved in Branched DNA Processing
Structure, 13, 2005
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1XTK
 | | structure of DECD to DEAD mutation of human UAP56 | | Descriptor: | BETA-MERCAPTOETHANOL, Probable ATP-dependent RNA helicase p47 | | Authors: | Shi, H, Cordin, O, Minder, C.M, Linder, P, Xu, R.M. | | Deposit date: | 2004-10-22 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the human ATP-dependent splicing and export factor UAP56
Proc.Natl.Acad.Sci.USA, 101, 2004
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1FUU
 | | YEAST INITIATION FACTOR 4A | | Descriptor: | YEAST INITIATION FACTOR 4A | | Authors: | Caruthers, J.M, Johnson, E.R, McKay, D.B. | | Deposit date: | 2000-09-15 | | Release date: | 2000-11-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1XTI
 | | Structure of Wildtype human UAP56 | | Descriptor: | ISOPROPYL ALCOHOL, Probable ATP-dependent RNA helicase p47 | | Authors: | Shi, H, Cordin, O, Minder, C.M, Linder, P, Xu, R.M. | | Deposit date: | 2004-10-21 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structure of the human ATP-dependent splicing and export factor UAP56
Proc.Natl.Acad.Sci.Usa, 101, 2004
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