3FMO

Crystal structure of the nucleoporin Nup214 in complex with the DEAD-box helicase Ddx19

Summary for 3FMO

Entry DOI	10.2210/pdb3fmo/pdb
Related	3FMP
Descriptor	Nuclear pore complex protein Nup214, ATP-dependent RNA helicase DDX19B, GLYCEROL, ... (5 entities in total)
Functional Keywords	nuclear porin, nuclear pore complex, nucleocytoplasmic transport, mrna export, protein interaction, helicase, beta-propeller, dead box, glycoprotein, mrna transport, nucleus, phosphoprotein, protein transport, proto-oncogene, translocation, transport, atp-binding, hydrolase, membrane, nucleotide-binding, rna-binding, protein transport-hydrolase complex, oncoprotein-hydrolase complex, oncoprotein/hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus, nuclear pore complex : P35658 Cytoplasm: Q9UMR2
Total number of polymer chains	2
Total formula weight	83888.94
Authors	Napetschnig, J.,Debler, E.W.,Blobel, G.,Hoelz, A. (deposition date: 2008-12-22, release date: 2009-05-19, Last modification date: 2023-09-06)
Primary citation	Napetschnig, J.,Kassube, S.A.,Debler, E.W.,Wong, R.W.,Blobel, G.,Hoelz, A. Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19. Proc.Natl.Acad.Sci.USA, 106:3089-3094, 2009 Cited by PubMed: 19208808 DOI: 10.1073/pnas.0813267106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.51 Å)

Structure validation