3FE2

Human DEAD-BOX RNA helicase DDX5 (P68), conserved domain I in complex with ADP

Summary for 3FE2

• Entry DOI: 10.2210/pdb3fe2/pdb
• Descriptor: Probable ATP-dependent RNA helicase DDX5, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: rna helicase, dead, adp, atp-binding, hydrolase, nucleotide-binding, rna-binding, helicase, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, spliceosome, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus, nucleolus: P17844
• Total number of polymer chains: 2
• Total formula weight: 55720.88

Authors

Karlberg, T.,Siponen, M.I.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wikstrom, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-11-27, release date: 2008-12-16, Last modification date: 2023-11-01)

• Primary citation: Schutz, P.,Karlberg, T.,van den Berg, S.,Collins, R.,Lehtio, L.,Hogbom, M.,Holmberg-Schiavone, L.,Tempel, W.,Park, H.W.,Hammarstrom, M.,Moche, M.,Thorsell, A.G.,Schuler, H.; Comparative Structural Analysis of Human DEAD-Box RNA Helicases; Plos One, 5:e12791-e12791, 2010; PubMed: 20941364; DOI: 10.1371/journal.pone.0012791

Experimental method

X-RAY DIFFRACTION (2.6 Å)