6BTZ
| Crystal structure of the PI3KC2alpha C2 domain in space group C121 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ... | 著者 | Chen, K.-E, Collins, B.M. | 登録日 | 2017-12-08 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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6BU0
| Crystal structure of the PI3KC2alpha C2 domain in complex with IP6 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Chen, K.-E, Collins, B.M. | 登録日 | 2017-12-08 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.427 Å) | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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3FBK
| Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A | 分子名称: | Regulator of G-protein signaling 3, SULFATE ION | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-11-19 | 公開日 | 2008-12-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A To be Published
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2NQ3
| Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase | 分子名称: | CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-10-30 | 公開日 | 2006-11-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase To be Published
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6BTY
| Crystal structure of the PI3KC2alpha C2 domain in space group P41212 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | 著者 | Chen, K.-E, Collins, B.M. | 登録日 | 2017-12-08 | 公開日 | 2018-10-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.678 Å) | 主引用文献 | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26, 2018
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4RJ9
| Structure of a plant specific C2 domain protein, OsGAP1 from rice | 分子名称: | C2 domain-containing protein-like, POTASSIUM ION | 著者 | Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. | 登録日 | 2014-10-08 | 公開日 | 2015-08-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). J.Biol.Chem., 290, 2015
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2NCE
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6ANJ
| Synaptotagmin-7, C2A domain | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | 登録日 | 2017-08-13 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6CXW
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4TS6
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2Q3X
| The RIM1alpha C2B domain | 分子名称: | CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ... | 著者 | Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J. | 登録日 | 2007-05-30 | 公開日 | 2007-08-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution. Biochemistry, 46, 2007
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4L1L
| Rat PKC C2 domain bound to CD | 分子名称: | CADMIUM ION, Protein kinase C alpha type, SULFATE ION | 著者 | Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I. | 登録日 | 2013-06-03 | 公開日 | 2013-08-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional. J.Am.Chem.Soc., 135, 2013
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4LDC
| Crystal Structure of DOC2B C2B domain | 分子名称: | CALCIUM ION, CITRATE ANION, Double C2-like domain-containing protein beta | 著者 | Giladi, M, Almagor, L, Hirsch, J.A. | 登録日 | 2013-06-24 | 公開日 | 2013-09-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.264 Å) | 主引用文献 | The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis. J.Mol.Biol., 425, 2013
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4LCV
| Crystal Structure of DOC2B C2A domain | 分子名称: | BETA-MERCAPTOETHANOL, CALCIUM ION, CITRATE ANION, ... | 著者 | Giladi, M, Almagor, L, Hirsch, J.A. | 登録日 | 2013-06-23 | 公開日 | 2013-09-11 | 最終更新日 | 2013-11-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis. J.Mol.Biol., 425, 2013
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6KXT
| BON1-C2B | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Protein BONZAI 1, SULFATE ION | 著者 | Wang, Q.C, Jiang, M.Q, Isupov, M.N, Sun, L.F, Wu, Y.K. | 登録日 | 2019-09-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Crystal Structure of an Arabidopsis Copine providing insights into this protein family To be published
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6LCY
| Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | 著者 | Zhang, Y, Zhang, X, Rao, F, Wang, C. | 登録日 | 2019-11-20 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis. Nat Metab, 3, 2021
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4LT7
| Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium | 分子名称: | CALCIUM ION, Rabphilin-3A | 著者 | Verdaguer, N, Ferrer-Orta, C, Buxaderas, M, Corbalan-Garcia, S, Perez-Sanchez, D, Guerrero-Valero, M, Luengo, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Guillen, J. | 登録日 | 2013-07-23 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4MJJ
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2K3H
| Structural determinants for Ca2+ and PIP2 binding by the C2A domain of rabphilin-3A | 分子名称: | CALCIUM ION, Rabphilin-3A | 著者 | Coudevylle, N, Montaville, P, Leonov, A, Zweckstetter, M, Becker, S. | 登録日 | 2008-05-08 | 公開日 | 2008-10-21 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Determinants for Ca2+ and Phosphatidylinositol 4,5-Bisphosphate Binding by the C2A Domain of Rabphilin-3A. J.Biol.Chem., 283, 2008
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2JQZ
| Solution Structure of the C2 domain of human Smurf2 | 分子名称: | E3 ubiquitin-protein ligase SMURF2 | 著者 | Wiesner, S, Ogunjimi, A.A, Wang, H, Rotin, D, Sicheri, F, Wrana, J.L, Forman-Kay, J.D. | 登録日 | 2007-06-15 | 公開日 | 2007-09-11 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain Cell(Cambridge,Mass.), 130, 2007
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2K45
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4NS0
| The C2A domain of Rabphilin 3A in complex with PI(4,5)P2 | 分子名称: | Rabphilin-3A, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | 登録日 | 2013-11-27 | 公開日 | 2013-12-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4NPK
| Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound | 分子名称: | CALCIUM ION, Extended synaptotagmin-2 | 著者 | Tomchick, D.R, Rizo, J, Xu, J. | 登録日 | 2013-11-21 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | 主引用文献 | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2. Structure, 22, 2014
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5A52
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5A51
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