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4XO0
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BU of 4xo0 by Molmil
Crystal structure of 5'-CTTATPPTAZZATAAG in a host-guest complex
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*T)-3'), DNA (5'-D(P*AP*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XPC
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BU of 4xpc by Molmil
Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*TP*AP*AP*G)-3'), ...
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XPE
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BU of 4xpe by Molmil
Crystal structure of 5'-CTTATGGGCCCATAAG in a host-guest complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*AP*AP*G)-3'), ...
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
1ZTT
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BU of 1ztt by Molmil
Netropsin bound to d(CTTAATTCGAATTAAG) in complex with MMLV RT catalytic fragment
分子名称: 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', NETROPSIN, ...
著者Goodwin, K.D, Long, E.C, Georgiadis, M.M.
登録日2005-05-27
公開日2005-08-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
1ZTW
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BU of 1ztw by Molmil
d(CTTAATTCGAATTAAG) complexed with Moloney Murine Leukemia Virus Reverse Transcriptase catalytic fragment
分子名称: CTTAATTC, GAATTAAG, Reverse transcriptase
著者Goodwin, K.D, Long, E.C, Georgiadis, M.M.
登録日2005-05-27
公開日2005-08-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
6MIH
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BU of 6mih by Molmil
Crystal structure of host-guest complex with PC hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIG
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BU of 6mig by Molmil
Crystal structure of host-guest complex with PB hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), Gag-Pol polyprotein
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIK
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BU of 6mik by Molmil
Crystal structure of host-guest complex with PP hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
7Z0Z
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BU of 7z0z by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant
分子名称: AbiK
著者Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M.
登録日2022-02-24
公開日2022-09-07
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
8BGJ
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BU of 8bgj by Molmil
Crystal structure of Reverse Transcriptase domain from Caloramator australicus CART-CAPP
分子名称: L(+)-TARTARIC ACID, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
著者Li, A.W.H, Doherty, A.J.
登録日2022-10-27
公開日2023-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Reverse transcriptases prime DNA synthesis.
Nucleic Acids Res., 51, 2023
8GH6
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BU of 8gh6 by Molmil
Bombyx mori R2 retrotransposon initiating target-primed reverse transcription
分子名称: 28S DNA bottom strand, 3' side, 5' side (priming strand), ...
著者Wilkinson, M.E, Zhang, F.
登録日2023-03-09
公開日2023-04-05
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription.
Science, 380, 2023
8IBY
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BU of 8iby by Molmil
Structure of R2 with 5'ORF
分子名称: 5'ORF RNA, Reverse transcriptase-like protein, ZINC ION
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBW
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BU of 8ibw by Molmil
Structure of R2 with 3'UTR and DNA in binding state
分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ...
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBX
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BU of 8ibx by Molmil
Structure of R2 with 3'UTR and DNA in unwinding state
分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ...
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBZ
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BU of 8ibz by Molmil
Structure of R2 with 5'ORF and 3'UTR
分子名称: 5ORF-linker-3UTR, Reverse transcriptase-like protein, ZINC ION
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
2R2U
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BU of 2r2u by Molmil
Co(III)bleomycinB2 bithiazole/C-terminal tail domain bound to d(ATTTAGTTAACTAAAT) complexed with MMLV RT catalytic fragment
分子名称: DNA (5'-D(*DAP*DTP*DTP*DTP*DAP*DGP*DT)-3'), DNA (5'-D(P*DTP*DAP*DCP*DTP*DAP*DAP*DAP*DT)-3'), N-(4-{[amino(imino)methyl]amino}butyl)-2,4'-bi-1,3-thiazole-4-carboxamide, ...
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2R
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BU of 2r2r by Molmil
d(ATTAGTTATAACTAAT) complexed with MMLV RT catalytic fragment
分子名称: DNA (5'-D(*DAP*DTP*DTP*DAP*DGP*DTP*DTP*DA)-3'), DNA (5'-D(P*DTP*DAP*DAP*DCP*DTP*DAP*DAP*DT)-3'), Reverse transcriptase
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2S
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BU of 2r2s by Molmil
Co(III)bleomycinB2 bound to d(ATTAGTTATAACTAAT) complexed with MMLV RT catalytic fragment
分子名称: BLEOMYCIN B2, COBALT (III) ION, DNA (5'-D(*DAP*DTP*DTP*DAP*DGP*DTP*DT)-3'), ...
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2T
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BU of 2r2t by Molmil
d(ATTTAGTTAACTAAAT) complexed with MMLV RT catalytic fragment
分子名称: DNA (5'-D(*DAP*DTP*DTP*DTP*DAP*DGP*DTP*DT)-3'), DNA (5'-D(P*DAP*DAP*DCP*DTP*DAP*DAP*DAP*DT)-3'), Reverse transcriptase
著者Goodwin, K.D, Lewis, M.A, Long, E.C, Georgiadis, M.M.
登録日2007-08-27
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1MML
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BU of 1mml by Molmil
MECHANISTIC IMPLICATIONS FROM THE STRUCTURE OF A CATALYTIC FRAGMENT OF MMLV REVERSE TRANSCRIPTASE
分子名称: MMLV REVERSE TRANSCRIPTASE
著者Georgiadis, M.M, Jessen, S.M, Ogata, C.M, Telesnitsky, A, Goff, S.P, Hendrickson, W.A.
登録日1995-07-18
公開日1995-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase.
Structure, 3, 1995
1N4L
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BU of 1n4l by Molmil
A DNA analogue of the polypurine tract of HIV-1
分子名称: 5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*TP*AP*AP*AP*AP*AP*G)-3', 5'-D(*CP*TP*TP*TP*TP*TP*AP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3', Reverse Transcriptase
著者Cote, M.L, Pflomm, M, Georgiadis, M.M.
登録日2002-10-31
公開日2003-06-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Staying Straight with A-tracts: A DNA Analog of the HIV-1 Polypurine Tract
J.Mol.Biol., 330, 2003
1NND
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BU of 1nnd by Molmil
Arginine 116 is Essential for Nucleic Acid Recognition by the Fingers Domain of Moloney Murine Leukemia Virus Reverse Transcriptase
分子名称: Reverse Transcriptase
著者Crowther, R.L, Remeta, D.P, Minetti, C.A, Das, D, Montano, S.P, Georgiadis, M.M.
登録日2003-01-13
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase
Proteins, 57, 2004
1D0E
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BU of 1d0e by Molmil
CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN
分子名称: 5'-D(*TP*TP*TP*CP*AP*TP*GP*CP*AP*TP*G)-3', REVERSE TRANSCRIPTASE
著者Najmudin, S, Cote, M.L, Sun, D, Yohannan, S, Montano, S.P, Gu, J, Georgiadis, M.M.
登録日1999-09-09
公開日2000-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain
J.Mol.Biol., 296, 2000
1D1U
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BU of 1d1u by Molmil
USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS
分子名称: DNA (5'-D(*AP*CP*GP*GP*CP*AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*TP*G)-3'), PROTEIN (REVERSE TRANSCRIPTASE)
著者Cote, M.L, Yohannan, S, Georgiadis, M.M.
登録日1999-09-21
公開日2000-04-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs.
Acta Crystallogr.,Sect.D, 56, 2000
2FJV
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BU of 2fjv by Molmil
RT29 Bound to D(CTTAATTCGAATTAAG) in complex with MMLV RT Catalytic Fragment
分子名称: 2-(4-(4-CARBAMIMIDOYLPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXIMIDAMIDE, 5'-D(*CP*TP*TP*AP*AP*TP*TP*C)-3', 5'-D(P*GP*AP*AP*TP*TP*AP*AP*G)-3', ...
著者Goodwin, K.D, Georgiadis, M.M.
登録日2006-01-03
公開日2006-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006

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