3D1M
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6PXV
| Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region. | 分子名称: | Insulin, Insulin receptor | 著者 | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | 登録日 | 2019-07-27 | 公開日 | 2019-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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6PYH
| Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved. | 分子名称: | Insulin-like growth factor 1 receptor, Insulin-like growth factor I | 著者 | Li, J, Choi, E, Yu, H.T, Bai, X.C. | 登録日 | 2019-07-29 | 公開日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of the activation of type 1 insulin-like growth factor receptor. Nat Commun, 10, 2019
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6PXW
| Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex. | 分子名称: | Insulin, Insulin receptor | 著者 | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | 登録日 | 2019-07-28 | 公開日 | 2019-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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3DI2
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3E0G
| Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ... | 著者 | Lupardus, P.J, Garcia, K.C. | 登録日 | 2008-07-31 | 公開日 | 2008-09-23 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol.Cell, 31, 2008
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3DI3
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3EW3
| the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor | 分子名称: | Prolactin, Prolactin receptor | 著者 | Broutin, I, Jomain, J.B, England, P, Goffin, V. | 登録日 | 2008-10-14 | 公開日 | 2009-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2. J.Biol.Chem., 285, 2010
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3F7P
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3FL7
| Crystal structure of the human ephrin A2 ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ... | 著者 | Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-18 | 公開日 | 2009-01-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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4K0V
| Structural basis for angiopoietin-1 mediated signaling initiation | 分子名称: | Angiopoietin-1, TEK tyrosine kinase variant | 著者 | Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A. | 登録日 | 2013-04-04 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4.51 Å) | 主引用文献 | Structural basis for angiopoietin-1-mediated signaling initiation. Proc.Natl.Acad.Sci.USA, 110, 2013
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2V5Y
| Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, SODIUM ION | 著者 | Aricescu, A.R, Siebold, C, Choudhuri, K, Chang, V.T, Lu, W, Davis, S.J, van der Merwe, P.A, Jones, E.Y. | 登録日 | 2007-07-11 | 公開日 | 2007-09-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism. Science, 317, 2007
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4Y5Y
| Diabody 330 complex with EpoR | 分子名称: | Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-03-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
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2W1N
| cohesin and fibronectin type-III double module construct from the Clostridium perfringens glycoside hydrolase GH84C | 分子名称: | ACETATE ION, O-GLCNACASE NAGJ | 著者 | Ficko-Blean, E, Gregg, K.J, Adams, J.J, Hehemann, J.H, Czjzek, M, Smith, S.J, Boraston, A.B. | 登録日 | 2008-10-17 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Portrait of an Enzyme: A Complete Structural Analysis of a Multi-Modular Beta-N-Acetylglucosaminidase from Clostridium Perfringens J.Biol.Chem., 284, 2009
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4Y5X
| Diabody 305 complex with EpoR | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-03-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
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4YH7
| Crystal structure of PTPdelta ectodomain in complex with IL1RAPL1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ... | 著者 | Yamagata, A, Fukai, S. | 登録日 | 2015-02-27 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation. Nat Commun, 6, 2015
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4Y61
| Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 2 | 著者 | Yamgata, A, Sato, Y, Goto-Ito, S, Uemura, T, Maeda, A, Shiroshima, T, Yoshida, T, Fukai, S. | 登録日 | 2015-02-12 | 公開日 | 2015-06-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.358 Å) | 主引用文献 | Structure of Slitrk2-PTP delta complex reveals mechanisms for splicing-dependent trans-synaptic adhesion. Sci Rep, 5, 2015
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4Y5V
| Diabody 305 complex with EpoR | 分子名称: | DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ... | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | 登録日 | 2015-02-12 | 公開日 | 2015-04-29 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160, 2015
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4BK5
| crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample) | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | 登録日 | 2013-04-22 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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2X10
| Crystal structure of the complete EphA2 ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 2 | 著者 | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | 登録日 | 2009-12-21 | 公開日 | 2010-03-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17, 2010
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4YFG
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4BKA
| crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | 登録日 | 2013-04-23 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (5.3 Å) | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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4YFD
| Crystal structure PTP delta Ig1-Fn2 in complex with IL-1RAcP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Receptor-type tyrosine-protein phosphatase delta | 著者 | Yamagata, A, Fukai, S. | 登録日 | 2015-02-25 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.253 Å) | 主引用文献 | Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation. Nat Commun, 6, 2015
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4BKF
| crystal structure of the human EphA4 ectodomain in complex with human ephrinB3 | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3 | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | 登録日 | 2013-04-24 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4.65 Å) | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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4BK4
| crystal structure of the human EphA4 ectodomain | 分子名称: | EPHRIN TYPE-A RECEPTOR 4 | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | 登録日 | 2013-04-22 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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