6DFM
| Crystal structure of human GRP78 in complex with 8-aminoadenosine | 分子名称: | (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, Endoplasmic reticulum chaperone BiP | 著者 | Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. | 登録日 | 2018-05-15 | 公開日 | 2019-05-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of human GRP78 in complex with 8-aminoadenosine To be Published
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1BA0
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6DWS
| Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | 分子名称: | 8-{[(2-chlorophenyl)methyl]amino}adenosine, Endoplasmic reticulum chaperone BiP, MAGNESIUM ION | 著者 | Chen, Y, Antoshchenko, T, Smil, D, Zepeda, C, Huang, Y, Park, H.W. | 登録日 | 2018-06-27 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol To Be Published
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1BA1
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1ATR
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6EOE
| Crystal structure of AMPylated GRP78 with nucleotide | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ... | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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6EOB
| Crystal structure of AMPylated GRP78 in apo form (Crystal form 1) | 分子名称: | 78 kDa glucose-regulated protein, PHOSPHATE ION | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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1BUP
| T13S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Sousa, M.C, Mckay, D.B. | 登録日 | 1998-09-03 | 公開日 | 1998-09-09 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change. Biochemistry, 37, 1998
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6EOC
| Crystal structure of AMPylated GRP78 in apo form (Crystal form 2) | 分子名称: | 78 kDa glucose-regulated protein, CITRATE ANION, SULFATE ION | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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6EOF
| Crystal structure of AMPylated GRP78 in ADP state | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Yan, Y, Preissler, S, Read, R.J, Ron, D. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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1BPR
| NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE | 分子名称: | DNAK | 著者 | Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P. | 登録日 | 1998-08-11 | 公開日 | 1999-03-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction. Biochemistry, 37, 1998
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3ATV
| Crystal structure of human Hsp70 NBD in the ADP-bound and Mg ion-free state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Heat shock 70 kDa protein 1A/1B, ... | 著者 | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2011-01-13 | 公開日 | 2011-12-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci., 20, 2011
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3ATU
| Crystal structure of human Hsp70 NBD in the ADP- and Mg ion-bound state | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, ... | 著者 | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2011-01-13 | 公開日 | 2011-12-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci., 20, 2011
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3AY9
| Crystal structure of human Hsp70 NBD in the ADP-, Mg ion-, and K ion-bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2011-05-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci., 20, 2011
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6FHK
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3C7N
| Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ... | 著者 | Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R. | 登録日 | 2008-02-07 | 公開日 | 2008-05-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.115 Å) | 主引用文献 | Structure of the Hsp110:Hsc70 nucleotide exchange machine Mol.Cell, 31, 2008
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1DKX
| THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 SELENOMETHIONYL CRYSTALS | 分子名称: | SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES) | 著者 | Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. | 登録日 | 1996-06-03 | 公開日 | 1996-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analysis of substrate binding by the molecular chaperone DnaK. Science, 272, 1996
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1DKZ
| THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 1 NATIVE CRYSTALS | 分子名称: | SUBSTRATE BINDING DOMAIN OF DNAK, SUBSTRATE PEPTIDE (7 RESIDUES) | 著者 | Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. | 登録日 | 1996-06-03 | 公開日 | 1996-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analysis of substrate binding by the molecular chaperone DnaK. Science, 272, 1996
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1DKY
| THE SUBSTRATE BINDING DOMAIN OF DNAK IN COMPLEX WITH A SUBSTRATE PEPTIDE, DETERMINED FROM TYPE 2 NATIVE CRYSTALS | 分子名称: | DNAK, PEPTIDE SUBSTRATE | 著者 | Zhu, X, Zhao, X, Burkholder, W.F, Gragerov, A, Ogata, C.M, Gottesman, M.E, Hendrickson, W.A. | 登録日 | 1996-06-03 | 公開日 | 1996-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural analysis of substrate binding by the molecular chaperone DnaK. Science, 272, 1996
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3D2E
| Crystal structure of a complex of Sse1p and Hsp70, Selenomethionine-labeled crystals | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Heat shock 70 kDa protein 1, ... | 著者 | Polier, S, Bracher, A. | 登録日 | 2008-05-08 | 公開日 | 2008-06-17 | 最終更新日 | 2017-07-26 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding. Cell(Cambridge,Mass.), 133, 2008
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3D2F
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3CQX
| Chaperone Complex | 分子名称: | BAG family molecular chaperone regulator 2, Heat shock cognate 71 kDa protein, SODIUM ION, ... | 著者 | Xu, Z, Nix, J.C, Misra, S. | 登録日 | 2008-04-03 | 公開日 | 2008-11-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2 Nat.Struct.Mol.Biol., 15, 2008
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3DPP
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3DPQ
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2QWQ
| Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form | 分子名称: | ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
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