2QWQ
Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form
Summary for 2QWQ
Entry DOI | 10.2210/pdb2qwq/pdb |
Related | 2QW9 2QWL 2QWM 2QWN 2QWO 2QWP 2QWR |
Descriptor | Heat shock cognate 71 kDa protein, Putative tyrosine-protein phosphatase auxilin, PHOSPHATE ION, ... (7 entities in total) |
Functional Keywords | chaperone-cochaperone complex, atp-binding, nucleotide-binding, nucleus, phosphorylation, stress response, hydrolase, protein phosphatase, sh3-binding, chaperone |
Biological source | Bos taurus (cattle) More |
Cellular location | Cytoplasm : P19120 |
Total number of polymer chains | 2 |
Total formula weight | 54881.96 |
Authors | Jiang, J.,Maes, E.G.,Wang, L.,Taylor, A.B.,Hinck, A.P.,Lafer, E.M.,Sousa, R. (deposition date: 2007-08-10, release date: 2007-12-18, Last modification date: 2021-10-20) |
Primary citation | Jiang, J.,Maes, E.G.,Taylor, A.B.,Wang, L.,Hinck, A.P.,Lafer, E.M.,Sousa, R. Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28:422-433, 2007 Cited by PubMed: 17996706DOI: 10.1016/j.molcel.2007.08.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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