PDB: 2407 resultsInfo pagesStatus searchChemie searchBIRD

---

4CI8	Crystal structure of the tandem atypical beta-propeller domain of EML1 Descriptor: ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1, SULFATE ION Authors: Richards, M.W, Bayliss, R. Deposit date: 2013-12-06 Release date: 2014-04-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Eml1 Reveals the Basis for Hsp90 Dependence of Oncogenic Eml4-Alk by Disruption of an Atypical Beta-Propeller Domain. Proc.Natl.Acad.Sci.USA, 111, 2014
4E5Z	Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair Descriptor: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ... Authors: Yeh, J.I, Du, S. Deposit date: 2012-03-15 Release date: 2012-08-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.22 Å) Cite: Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc.Natl.Acad.Sci.USA, 109, 2012
4E54	Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair Descriptor: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ... Authors: Yeh, J.I, Du, S. Deposit date: 2012-03-14 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc.Natl.Acad.Sci.USA, 109, 2012
4FHM	Nup37-Nup120(aa1-961) complex from Schizosaccharomyces pombe Descriptor: NUCLEOPORIN NUP37, Nucleoporin nup120 Authors: Bilokapic, S, Schwartz, T.U. Deposit date: 2012-06-06 Release date: 2012-09-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4.339 Å) Cite: Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex. Proc.Natl.Acad.Sci.USA, 109, 2012
4GGD	Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Descriptor: Cell division cycle protein 20 homolog, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Authors: Luo, X, Tian, W, Tomchick, D.R. Deposit date: 2012-08-06 Release date: 2012-11-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.435 Å) Cite: Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc.Natl.Acad.Sci.USA, 109, 2012
4U7A	The carboxy-terminal domain of Erb1 is a seven-bladed beta-propeller that binds RNA. Descriptor: 1,2-ETHANEDIOL, ETHANOL, GLYCEROL, ... Authors: Wegrecki, M, Bravo, J. Deposit date: 2014-07-30 Release date: 2015-04-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The Carboxy-Terminal Domain of Erb1 Is a Seven-Bladed -Propeller that Binds RNA. Plos One, 10, 2015
4UI9	Atomic structure of the human Anaphase-Promoting Complex Descriptor: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... Authors: Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. Deposit date: 2015-03-27 Release date: 2015-06-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination Nature, 522, 2015
5TEF	Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, GLYCEROL, Gem-associated protein 5, ... Authors: Chao, X, Tempel, W, Bian, C, He, H, Cerovina, T, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2016-09-21 Release date: 2016-10-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev., 30, 2016
5TEE	Crystal structure of Gemin5 WD40 repeats in apo form Descriptor: GLYCEROL, Gem-associated protein 5, SODIUM ION, ... Authors: Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Walker, J.R, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2016-09-21 Release date: 2016-10-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev., 30, 2016
5TDH	The crystal structure of the dominant negative mutant G protein alpha(i)-1-beta-1-gamma-2 G203A/A326S Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Liu, P, Jia, M.-Z, Zhou, X.E, de Waal, P.W, Dickson, B.M, Liu, B, Hou, L, Yin, Y.-T, Kang, Y.-Y, Shi, Y, Melcher, K, Xu, H.E, Jiang, Y. Deposit date: 2016-09-19 Release date: 2016-11-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3 Å) Cite: The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer Acta Pharmacol.Sin., 37, 2016
5THA	Gemin5 WD40 repeats in complex with a guanosyl moiety Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, Gem-associated protein 5, UNKNOWN ATOM OR ION Authors: Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2016-09-29 Release date: 2016-10-19 Last modified: 2022-12-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev., 30, 2016
5TQR	ctPRC2 in an autoinhibited conformation bound to S-adenosylmethionine Descriptor: Histone-lysine N-methyltransferase EZH2, Polycomb protein SUZ12, Polycomb Protein EED, ... Authors: Bratkowski, M.A, Liu, X. Deposit date: 2016-10-24 Release date: 2017-06-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.571 Å) Cite: Polycomb repressive complex 2 in an autoinhibited state. J. Biol. Chem., 292, 2017
5U62	Crystal structure of EED in complex with H3K27Me3 peptide and 6-(benzo[d][1,3]dioxol-4-ylmethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine Descriptor: (6S)-6-[(2H-1,3-benzodioxol-4-yl)methyl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine, GLYCEROL, Histone-lysine N-methyltransferase EZH2, ... Authors: Bussiere, D, Shu, W. Deposit date: 2016-12-07 Release date: 2017-01-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase. J. Med. Chem., 60, 2017
5U5T	Crystal structure of EED in complex with H3K27Me3 peptide and 3-(benzo[d][1,3]dioxol-4-ylmethyl)piperidine-1-carboximidamide Descriptor: (3R)-3-[(2H-1,3-benzodioxol-4-yl)methyl]piperidine-1-carboximidamide, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ... Authors: Bussiere, D, Shu, W. Deposit date: 2016-12-07 Release date: 2017-01-11 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase. J. Med. Chem., 60, 2017
5V4B	Crystal structure of the Skp1-FBXW7-DISC1 complex Descriptor: DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ... Authors: Li, Y, Baillie, G.S, Hao, B. Deposit date: 2017-03-08 Release date: 2017-09-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Mol. Psychiatry, 23, 2018
5VH9	Cryo-EM structure of yeast cytoplasmic dynein-1 with Lis1 and ATP Descriptor: Dynein heavy chain, cytoplasmic, Nuclear distribution protein PAC1 Authors: Cianfrocco, M.A, DeSantis, M.E, Htet, Z.M, Tran, P.T, Reck-Peterson, S.L, Leschziner, A.E. Deposit date: 2017-04-12 Release date: 2017-09-06 Last modified: 2020-01-01 Method: ELECTRON MICROSCOPY (7.7 Å) Cite: Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein. Cell, 170, 2017
4XYH	Wild-type full length Mis16 in Schizosaccharomyces japonicus Descriptor: Kinetochore protein Mis16 Authors: An, S, Kim, H, Cho, U.-S. Deposit date: 2015-02-02 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp. J.Mol.Biol., 427, 2015
4XYI	Mis16 with H4 peptide Descriptor: Histone H4, Kinetochore protein Mis16 Authors: An, S, Kim, H, Cho, U.-S. Deposit date: 2015-02-02 Release date: 2016-02-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Mis16 Independently Recognizes Histone H4 and the CENP-ACnp1-Specific Chaperone Scm3sp. J.Mol.Biol., 427, 2015
4YCZ	Y-COMPLEX HUB (NUP85-NUP120-NUP145C-SEC13 COMPLEX) FROM M. THERMOPHILA (A.K.A. T. HETEROTHALLICA) Descriptor: Fusion Protein of Sec13 and Nup145C, Nup120, Nup85 Authors: Kelley, K, Knockenhauer, K.E, Schwartz, T.U. Deposit date: 2015-02-20 Release date: 2015-04-01 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Atomic structure of the Y complex of the nuclear pore. Nat.Struct.Mol.Biol., 22, 2015
5A9Q	Human nuclear pore complex Descriptor: NUCLEAR PORE COMPLEX PROTEIN NUP107, NUCLEAR PORE COMPLEX PROTEIN NUP133, NUCLEAR PORE COMPLEX PROTEIN NUP155, ... Authors: von Appen, A, Kosinski, J, Sparks, L, Ori, A, DiGuilio, A, Vollmer, B, Mackmull, M, Banterle, N, Parca, L, Kastritis, P, Buczak, K, Mosalaganti, S, Hagen, W, Andres-Pons, A, Lemke, E.A, Bork, P, Antonin, W, Glavy, J.S, Bui, K.H, Beck, M. Deposit date: 2015-07-22 Release date: 2015-09-30 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (23 Å) Cite: In Situ Structural Analysis of the Human Nuclear Pore Complex Nature, 526, 2015
5BJS	Apo ctPRC2 in an autoinhibited state Descriptor: Histone-lysine N-methyltransferase EZH2, Polycomb protein SUZ12, Polycomb Protein EED, ... Authors: Bratkowski, M.A, Liu, X. Deposit date: 2016-10-22 Release date: 2017-06-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.189 Å) Cite: Polycomb repressive complex 2 in an autoinhibited state. J. Biol. Chem., 292, 2017
5C9Z	Crystal structure of PRMT5:MEP50 with EPZ015866 and sinefungin Descriptor: 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]pyridine-4-carboxamide, GLYCEROL, Methylosome protein 50, ... Authors: Boriack-Sjodin, P.A. Deposit date: 2015-06-29 Release date: 2016-06-29 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Crystal structure of PRMT5/MEP50 complex with sinefungin and 15866 To Be Published
5CVL	WDR48 (UAF-1), residues 2-580 Descriptor: GOLD ION, PHOSPHATE ION, WD repeat-containing protein 48 Authors: HARRIS, S.F, YIN, J. Deposit date: 2015-07-27 Release date: 2015-10-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
5CXB	Structure of Ytm1 bound to the C-terminal domain of Erb1 in P21 21 2 space group Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Wegrecki, M, Bravo, J. Deposit date: 2015-07-28 Release date: 2015-11-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
5CXC	Structure of Ytm1 bound to the C-terminal domain of Erb1 in P 65 2 2 space group Descriptor: CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 Authors: Wegrecki, M, Bravo, J. Deposit date: 2015-07-28 Release date: 2015-10-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015

<9101112131415161718192021222324>