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5C9Z

Crystal structure of PRMT5:MEP50 with EPZ015866 and sinefungin

Summary for 5C9Z
Entry DOI10.2210/pdb5c9z/pdb
Related4X60
DescriptorProtein arginine N-methyltransferase 5, Methylosome protein 50, SINEFUNGIN, ... (6 entities in total)
Functional Keywordsmethyltransferase protein-inhibitor complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
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Cellular locationCytoplasm : O14744
Nucleus: Q9BQA1
Total number of polymer chains2
Total formula weight112479.99
Authors
Boriack-Sjodin, P.A. (deposition date: 2015-06-29, release date: 2016-06-29)
Primary citationBoriack-Sjodin, P.A.
Crystal structure of PRMT5/MEP50 complex with sinefungin and 15866
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.36 Å)
Structure validation

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