4GGD
Structural analysis of human Cdc20 supports multisite degron recognition by APC/C.
Summary for 4GGD
| Entry DOI | 10.2210/pdb4ggd/pdb |
| Related | 4GGA 4GGC |
| Descriptor | Cell division cycle protein 20 homolog, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (3 entities in total) |
| Functional Keywords | cell cycle, mitosis, securin, ubiquitination, wd40 |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : Q12834 Cytoplasm: O60566 |
| Total number of polymer chains | 4 |
| Total formula weight | 100512.73 |
| Authors | Luo, X.,Tian, W.,Tomchick, D.R. (deposition date: 2012-08-06, release date: 2012-11-07, Last modification date: 2024-02-28) |
| Primary citation | Tian, W.,Li, B.,Warrington, R.,Tomchick, D.R.,Yu, H.,Luo, X. Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc.Natl.Acad.Sci.USA, 109:18419-18424, 2012 Cited by PubMed: 23091007DOI: 10.1073/pnas.1213438109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.435 Å) |
Structure validation
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