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PDB: 170 results

4WHE
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BU of 4whe by Molmil
Crystal structure of E. coli phage shock protein A (PspA 1-144)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phage shock protein A
Authors:Parthier, C, Schoepfel, M, Stubbs, M.T, Osadnik, H, Brueser, T.
Deposit date:2014-09-22
Release date:2015-09-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:PspF-binding domain PspA1-144 and the PspAF complex: New insights into the coiled-coil-dependent regulation of AAA+ proteins.
Mol.Microbiol., 98, 2015
6GV1
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BU of 6gv1 by Molmil
Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment
Descriptor: Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, ...
Authors:Nagarathinam, K, Parthier, C, Stubbs, M.T, Tanabe, M.
Deposit date:2018-06-20
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism.
Nat Commun, 9, 2018
1A5I
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BU of 1a5i by Molmil
CATALYTIC DOMAIN OF VAMPIRE BAT (DESMODUS ROTUNDUS) SALIVA PLASMINOGEN ACTIVATOR IN COMPLEX WITH EGR-CMK (GLU-GLY-ARG CHLOROMETHYL KETONE)
Descriptor: L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, PLASMINOGEN ACTIVATOR
Authors:Renatus, M, Stubbs, M.T, Bode, W.
Deposit date:1998-02-17
Release date:1999-03-23
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage.
Biochemistry, 36, 1997
1BTH
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BU of 1bth by Molmil
STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR, THROMBIN
Authors:Van De Locht, A, Bode, W, Stubbs, M.T.
Deposit date:1996-12-03
Release date:1997-12-24
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin.
EMBO J., 16, 1997
2BMA
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BU of 2bma by Molmil
The crystal structure of Plasmodium falciparum glutamate dehydrogenase, a putative target for novel antimalarial drugs
Descriptor: GLUTAMATE DEHYDROGENASE (NADP+)
Authors:Werner, C, Stubbs, M.T, Krauth-Siege, R.L, Klebe, G.
Deposit date:2005-03-10
Release date:2005-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Crystal Structure of Plasmodium Falciparum Glutamate Dehydrogenase, a Putative Target for Novel Antimalarial Drugs
J.Mol.Biol., 349, 2005
1A5H
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BU of 1a5h by Molmil
CATALYTIC DOMAIN OF HUMAN TWO-CHAIN TISSUE PLASMINOGEN ACTIVATOR COMPLEX OF A BIS-BENZAMIDINE
Descriptor: 2,7-BIS-(4-AMIDINOBENZYLIDENE)-CYCLOHEPTAN-1-ONE, TISSUE PLASMINOGEN ACTIVATOR
Authors:Renatus, M, Bode, W, Stubbs, M.T.
Deposit date:1998-02-17
Release date:1999-04-20
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors.
J.Biol.Chem., 272, 1997
5MY4
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BU of 5my4 by Molmil
Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with human Abeta-pE3-12PEGb
Descriptor: Fab c#17 heavy chain, Fab c#17 light chain, Pyroglutamate-Abeta pE3-12-PEGb
Authors:Parthier, C, Piechotta, A, Stubbs, M.T.
Deposit date:2017-01-25
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy.
J. Biol. Chem., 292, 2017
5MYK
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BU of 5myk by Molmil
Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with murine Abeta-pE3-18PEGb
Descriptor: Amyloid beta A4 protein, Fab c#17 heavy chain, Fab c#17 light chain
Authors:Parthier, C, Piechotta, A, Stubbs, M.T.
Deposit date:2017-01-26
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy.
J. Biol. Chem., 292, 2017
5MYO
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BU of 5myo by Molmil
Structure of Pyroglutamate-Abeta-specific Fab c#6 in complex with human Abeta-pE3-12-PEGb
Descriptor: Amyloid beta A4 protein, Fab c#6 heavy chain, Fab c#6 light chain, ...
Authors:Parthier, C, Piechotta, A, Stubbs, M.T.
Deposit date:2017-01-27
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy.
J. Biol. Chem., 292, 2017
5MYX
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BU of 5myx by Molmil
Structure of Pyroglutamate-Abeta-specific Fab c#24 in complex with human Abeta-pE3-18
Descriptor: Fab c#24 heavy chain, Fab c#24 light chain, Pyroglutamate-Abeta pE3-18
Authors:Parthier, C, Piechotta, A, Stubbs, M.T.
Deposit date:2017-01-30
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy.
J. Biol. Chem., 292, 2017
6QQL
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BU of 6qql by Molmil
Crystal structure of Porphyromonas gingivalis glutaminyl cyclase
Descriptor: Glutamine cyclotransferase, ZINC ION
Authors:Linnert, M, Piechotta, A, Parthier, C, Taudte, N, Kolenko, P, Rahfeld, J, Potempa, J, Stubbs, M.T.
Deposit date:2019-02-18
Release date:2019-03-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.814 Å)
Cite:Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis.
J.Biol.Chem., 296, 2021
6SHT
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BU of 6sht by Molmil
Molecular structure of mouse apoferritin resolved at 2.7 Angstroms with the Glacios cryo-microscope
Descriptor: FE (III) ION, Ferritin heavy chain, MAGNESIUM ION
Authors:Hamdi, F, Tueting, C, Semchonok, D, Kyrilis, F, Meister, A, Skalidis, I, Schmidt, L, Parthier, C, Stubbs, M.T, Kastritis, P.L.
Deposit date:2019-08-08
Release date:2020-05-13
Last modified:2020-05-27
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:2.7 angstrom cryo-EM structure of vitrified M. musculus H-chain apoferritin from a compact 200 keV cryo-microscope.
Plos One, 15, 2020
6QRO
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BU of 6qro by Molmil
Crystal structure of Tannerella forsythia glutaminyl cyclase
Descriptor: Glutamine cyclotransferase, SULFATE ION, ZINC ION
Authors:Linnert, M, Piechotta, A, Parthier, C, Taudte, N, Kolenko, P, Rahfeld, J, Potempa, J, Stubbs, M.T.
Deposit date:2019-02-19
Release date:2019-03-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis.
J.Biol.Chem., 296, 2021
7YWC
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BU of 7ywc by Molmil
Enzyme of biosynthetic pathway
Descriptor: (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, Chorismate dehydratase, GLYCEROL
Authors:Archna, A, Breithaupt, C, Stubbs, M.T.
Deposit date:2022-02-12
Release date:2022-10-26
Last modified:2022-11-30
Method:X-RAY DIFFRACTION (1.917 Å)
Cite:Mechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis.
J.Biol.Chem., 298, 2022
2JDF
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BU of 2jdf by Molmil
Human gamma-B crystallin
Descriptor: GAMMA CRYSTALLIN B
Authors:Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U.
Deposit date:2007-01-08
Release date:2007-07-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
J.Mol.Biol., 372, 2007
4NIW
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BU of 4niw by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) orthorhombic form
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NIV
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BU of 4niv by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) trigonal form
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NIY
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BU of 4niy by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) complexed to YRH-ecotin (M84Y/M85R/A86H ecotin)
Descriptor: CALCIUM ION, Cationic trypsin, Ecotin, ...
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NIX
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BU of 4nix by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) orthorhombic form, zinc-bound
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
3LN9
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BU of 3ln9 by Molmil
Crystal structure of the fibril-specific B10 antibody fragment
Descriptor: CITRATE ANION, GLYCEROL, Immunoglobulin heavy chain antibody variable domain B10, ...
Authors:Parthier, C, Morgado, I, Stubbs, M.T, Faendrich, M.
Deposit date:2010-02-02
Release date:2010-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions.
J.Mol.Biol., 2010
3LUO
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BU of 3luo by Molmil
Crystal Structure and functional characterization of the thermophilic prolyl isomerase and chaperone SlyD
Descriptor: Peptidyl-prolyl cis-trans isomerase, Suc-Ala-Leu-Pro-Phe-pNA, ZINC ION
Authors:Loew, C, Neumann, P, Weininger, U, Stubbs, M.T, Balbach, J.
Deposit date:2010-02-18
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus
J.Mol.Biol., 398, 2010
3NOK
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BU of 3nok by Molmil
Crystal structure of Myxococcus xanthus Glutaminyl Cyclase
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ...
Authors:Parthier, C, Carrillo, D.R, Stubbs, M.T.
Deposit date:2010-06-25
Release date:2010-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Biol.Chem., 391, 2010
3NOL
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BU of 3nol by Molmil
Crystal structure of Zymomonas mobilis Glutaminyl Cyclase (trigonal form)
Descriptor: CALCIUM ION, GLYCEROL, Glutamine cyclotransferase, ...
Authors:Parthier, C, Carrillo, D.R, Stubbs, M.T.
Deposit date:2010-06-25
Release date:2010-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Biol.Chem., 391, 2010
3NOM
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BU of 3nom by Molmil
Crystal Structure of Zymomonas mobilis Glutaminyl Cyclase (monoclinic form)
Descriptor: CALCIUM ION, GLYCEROL, Glutamine cyclotransferase, ...
Authors:Parthier, C, Carrillo, D.R, Stubbs, M.T.
Deposit date:2010-06-25
Release date:2010-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
Biol.Chem., 391, 2010
2JDG
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BU of 2jdg by Molmil
Affilin based on HUMAN GAMMA-B CRYSTALLIN
Descriptor: GAMMA CRYSTALLIN B
Authors:Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U.
Deposit date:2007-01-08
Release date:2007-07-24
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
J.Mol.Biol., 372, 2007

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