4A5P
| Structure of the Shigella flexneri MxiA protein | Descriptor: | 1,2-ETHANEDIOL, PROTEIN MXIA | Authors: | Abrusci, P, Vegara-Irigaray, M, Johnson, S, Roversi, P, Friede, M.E, Deane, J.E, Tang, C.M, Lea, S.M. | Deposit date: | 2011-10-26 | Release date: | 2012-11-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Architecture of the major component of the type III secretion system export apparatus. Nat.Struct.Mol.Biol., 20, 2013
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2J0O
| Shigella Flexneri IpaD | Descriptor: | GLYCEROL, INVASIN IPAD | Authors: | Johnson, S, Roversi, P, Lea, S.M. | Deposit date: | 2006-08-04 | Release date: | 2006-11-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD. J. Biol. Chem., 282, 2007
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2IXR
| BipD of Burkholderia Pseudomallei | Descriptor: | MEMBRANE ANTIGEN | Authors: | Roversi, P, Johnson, S, Field, T, Deane, J.E, Galyov, E.E, Lea, S.M. | Deposit date: | 2006-07-10 | Release date: | 2006-11-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd. J.Biol.Chem., 282, 2007
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2J0N
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2J9T
| BipD of Burkholderia Pseudomallei | Descriptor: | BORIC ACID, CITRATE ANION, MEMBRANE ANTIGEN | Authors: | Johnson, S, Roversi, P, Field, T, Deane, J.E, Galyov, E, Lea, S.M. | Deposit date: | 2006-11-16 | Release date: | 2006-11-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd. J.Biol.Chem., 282, 2007
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8GL6
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8GLM
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8GLK
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8GLN
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8GL8
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8GLJ
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1H8T
| Echovirus 11 | Descriptor: | 12-AMINO-DODECANOIC ACID, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... | Authors: | Stuart, A, McKee, T, Williams, P.A, Harley, C, Stuart, D.I, Brown, T.D.K, Lea, S.M. | Deposit date: | 2001-02-15 | Release date: | 2002-07-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection J.Virol., 76, 2002
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7NQK
| Cryo-EM structure of the mammalian peptide transporter PepT2 | Descriptor: | Solute carrier family 15 member 2, nanobody | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | Deposit date: | 2021-03-01 | Release date: | 2021-07-07 | Last modified: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals. Sci Adv, 7, 2021
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7NVG
| Salmonella flagellar basal body refined in C1 map | Descriptor: | Basal-body rod modification protein FlgD, Flagellar L-ring protein, Flagellar M-ring protein, ... | Authors: | Johnson, S, Furlong, E, Lea, S.M. | Deposit date: | 2021-03-15 | Release date: | 2021-05-05 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular structure of the intact bacterial flagellar basal body. Nat Microbiol, 6, 2021
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7NVH
| Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis | Descriptor: | 2-decyl-2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, Trehalose monomycolate exporter MmpL3 | Authors: | Adams, O, Deme, J.C, Parker, J.L, Lea, S.M, Newstead, S. | Deposit date: | 2021-03-15 | Release date: | 2021-06-16 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target. Structure, 29, 2021
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7OXR
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7OXP
| Cryo-EM structure of yeast Sei1 | Descriptor: | BJ4_G0032880.mRNA.1.CDS.1,BJ4_G0032880.mRNA.1.CDS.1 | Authors: | Deme, J.C, Lea, S.M. | Deposit date: | 2021-06-22 | Release date: | 2021-10-13 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex. Nat Commun, 12, 2021
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7P9U
| Cryo EM structure of System XC- in complex with glutamate | Descriptor: | 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter, GLUTAMIC ACID | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | Deposit date: | 2021-07-28 | Release date: | 2021-11-17 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular basis for redox control by the human cystine/glutamate antiporter system xc . Nat Commun, 12, 2021
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7P9V
| Cryo EM structure of System XC- | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | Deposit date: | 2021-07-28 | Release date: | 2021-11-17 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for redox control by the human cystine/glutamate antiporter system xc . Nat Commun, 12, 2021
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2V6L
| Molecular Model of a Type III Secretion System Needle | Descriptor: | MXIH | Authors: | Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Daniell, S, Booy, F, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M. | Deposit date: | 2007-07-19 | Release date: | 2007-07-31 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | Molecular model of a type III secretion system needle: Implications for host-cell sensing. Proc. Natl. Acad. Sci. U.S.A., 103, 2006
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6X9O
| High resolution cryoEM structure of huntingtin in complex with HAP40 | Descriptor: | 40-kDa huntingtin-associated protein, Huntingtin | Authors: | Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-03 | Release date: | 2020-06-17 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. Commun Biol, 4, 2021
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6YS8
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8HCN
| CryoEM Structure of Klebsiella pneumoniae UreD/urease complex | Descriptor: | Urease accessory protein UreD, Urease subunit alpha, Urease subunit beta, ... | Authors: | Nim, Y.S, Fong, I.Y.H, Deme, J, Tsang, K.L, Caesar, J, Johnson, S, Wong, K.B, Lea, S.M. | Deposit date: | 2022-11-02 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Delivering a toxic metal to the active site of urease. Sci Adv, 9, 2023
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8HC1
| CryoEM structure of Helicobacter pylori UreFD/urease complex | Descriptor: | Urease accessory protein UreF, Urease accessory protein UreH, Urease subunit alpha, ... | Authors: | Nim, Y.S, Fong, I.Y.H, Deme, J, Tsang, K.L, Caesar, J, Johnson, S, Wong, K.B, Lea, S.M. | Deposit date: | 2022-11-01 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Delivering a toxic metal to the active site of urease. Sci Adv, 9, 2023
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6H3J
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