7OXR
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7OXP
| Cryo-EM structure of yeast Sei1 | Descriptor: | BJ4_G0032880.mRNA.1.CDS.1,BJ4_G0032880.mRNA.1.CDS.1 | Authors: | Deme, J.C, Lea, S.M. | Deposit date: | 2021-06-22 | Release date: | 2021-10-13 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex. Nat Commun, 12, 2021
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6H3I
| Structural snapshots of the Type 9 protein translocon | Descriptor: | Peptidyl-prolyl cis-trans isomerase, PorV, Protein involved in gliding motility SprA | Authors: | Deme, J.C, Lea, S.M. | Deposit date: | 2018-07-18 | Release date: | 2018-11-07 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Type 9 secretion system structures reveal a new protein transport mechanism. Nature, 564, 2018
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6H3J
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7YXY
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7YXX
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8GL8
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8UCS
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8GL6
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8GLJ
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8GLK
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8GLN
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8GLM
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2MME
| Hybrid structure of the Shigella flexneri MxiH Type three secretion system needle | Descriptor: | MxiH | Authors: | Demers, J.P, Habenstein, B, Loquet, A, Vasa, S.K, Becker, S, Baker, D, Lange, A, Sgourakis, N.G. | Deposit date: | 2014-03-14 | Release date: | 2014-10-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.7 Å), SOLID-STATE NMR | Cite: | High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy. Nat Commun, 5, 2014
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7NVH
| Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis | Descriptor: | Lauryl Maltose Neopentyl Glycol, Trehalose monomycolate exporter MmpL3 | Authors: | Adams, O, Deme, J.C, Parker, J.L, Lea, S.M, Newstead, S. | Deposit date: | 2021-03-15 | Release date: | 2021-06-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target. Structure, 29, 2021
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7AKV
| The cryo-EM structure of the Vag8-C1 inhibitor complex | Descriptor: | Plasma protease C1 inhibitor, Vag8 | Authors: | Johnson, S, Lea, S.M, Deme, J.C, Furlong, E, Dhillon, A. | Deposit date: | 2020-10-02 | Release date: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex. Mbio, 12, 2021
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7SB2
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7SAT
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7SAZ
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7SAU
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7SAX
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6X9O
| High resolution cryoEM structure of huntingtin in complex with HAP40 | Descriptor: | 40-kDa huntingtin-associated protein, Huntingtin | Authors: | Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2020-06-03 | Release date: | 2020-06-17 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. Commun Biol, 4, 2021
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6YSF
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6YSL
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7NQK
| Cryo-EM structure of the mammalian peptide transporter PepT2 | Descriptor: | Solute carrier family 15 member 2, nanobody | Authors: | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | Deposit date: | 2021-03-01 | Release date: | 2021-07-07 | Last modified: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals. Sci Adv, 7, 2021
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