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7ASG
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BU of 7asg by Molmil
TGFBIp mutant R555W
Descriptor: Transforming growth factor-beta-induced protein ig-h3
Authors:Nielsen, N.S, Gadeberg, T.A.F, Andersen, G.R.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
7Q61
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BU of 7q61 by Molmil
Structure of TEV conjugated A2ML1 (A2ML1-TC)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin-like protein 1
Authors:Nielsen, N.S, Zarantonello, A, Andersen, G.R.
Deposit date:2021-11-05
Release date:2022-04-20
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7Q62
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BU of 7q62 by Molmil
Structure of TEV cleaved A2ML1 dimer (A2ML1-TT dimer)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin-like protein 1
Authors:Nielsen, N.S, Zarantonello, A, Andersen, G.R.
Deposit date:2021-11-05
Release date:2022-04-20
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7Q60
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BU of 7q60 by Molmil
Structure of TEV cleaved A2ML1 (A2ML1-TE)
Descriptor: Alpha-2-macroglobulin-like protein 1
Authors:Nielsen, N.S, Zarantonello, A, Andersen, G.R.
Deposit date:2021-11-05
Release date:2022-04-20
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7ASC
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BU of 7asc by Molmil
TGFBIp mutant A546T
Descriptor: Transforming growth factor-beta-induced protein ig-h3
Authors:Andersen, G.R, Nielsen, N.S, Gadeberg, T.A.F.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
7AS7
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BU of 7as7 by Molmil
Crystal structure of the GCD-associated TGFBIp mutant R124H
Descriptor: Transforming growth factor-beta-induced protein ig-h3
Authors:Andersen, G.R, Gadeberg, T.A.F, Nielsen, N.S, Enghild, J.J.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
7Q1Y
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BU of 7q1y by Molmil
X-ray structure of human A2ML1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin-like protein 1, ...
Authors:Andersen, G.R, Zarantonello, A, Enghild, J.J, Nielsen, N.S.
Deposit date:2021-10-22
Release date:2022-04-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7Q5Z
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BU of 7q5z by Molmil
Cryo-EM structure of native human A2ML1
Descriptor: Alpha-2-macroglobulin-like protein 1
Authors:Zarantonello, A, Nielsen, N.S, Andersen, G.R.
Deposit date:2021-11-05
Release date:2022-04-20
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
5NV6
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BU of 5nv6 by Molmil
Structure of human transforming growth factor beta-induced protein (TGFBIp).
Descriptor: ACETATE ION, Transforming growth factor-beta-induced protein ig-h3
Authors:Garcia-Castellanos, R, Nielsen, S.N, Runager, K, Thogersen, B.I, Goulas, T, Enghild, J.J, Gomis-Ruth, F.X.
Deposit date:2017-05-03
Release date:2017-08-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural and Functional Implications of Human Transforming Growth Factor beta-Induced Protein, TGFBIp, in Corneal Dystrophies.
Structure, 25, 2017

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