7Q5Z

Cryo-EM structure of native human A2ML1

Summary for 7Q5Z

• Entry DOI: 10.2210/pdb7q5z/pdb
• EMDB information: 13847
• Descriptor: Alpha-2-macroglobulin-like protein 1 (1 entity in total)
• Functional Keywords: protease, inhibitor, thioester, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 159339.28

Authors

Zarantonello, A.,Nielsen, N.S.,Andersen, G.R. (deposition date: 2021-11-05, release date: 2022-04-20, Last modification date: 2022-11-02)

• Primary citation: Nielsen, N.S.,Zarantonello, A.,Harwood, S.L.,Jensen, K.T.,Kjoge, K.,Thogersen, I.B.,Schauser, L.,Karlsen, J.L.,Andersen, G.R.,Enghild, J.J.; Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.; Nat Commun, 13:3033-3033, 2022; PubMed: 35641520; DOI: 10.1038/s41467-022-30758-x

Experimental method

ELECTRON MICROSCOPY (3.25 Å)