7Q5Z

Cryo-EM structure of native human A2ML1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004866	molecular_function	endopeptidase inhibitor activity
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0030414	molecular_function	peptidase inhibitor activity
A	0052548	biological_process	regulation of endopeptidase activity
A	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00477
Number of Residues	9
Details	ALPHA_2_MACROGLOBULIN Alpha-2-macroglobulin family thiolester region signature. PsGCGEQnM

Chain	Residue	Details
A	PRO967-MET975

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN120
A	ASN281
A	ASN409
A	ASN857
A	ASN1020

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Isoglutamyl cysteine thioester (Cys-Gln) => ECO:0000250|UniProtKB:P01023

Chain	Residue	Details
A	CYS970
A	GLN973

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