7Q61
Structure of TEV conjugated A2ML1 (A2ML1-TC)
Summary for 7Q61
| Entry DOI | 10.2210/pdb7q61/pdb |
| EMDB information | 13849 |
| Descriptor | Alpha-2-macroglobulin-like protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | protease inhibitor, thioester, immune system |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 160851.71 |
| Authors | Nielsen, N.S.,Zarantonello, A.,Andersen, G.R. (deposition date: 2021-11-05, release date: 2022-04-20, Last modification date: 2022-11-02) |
| Primary citation | Nielsen, N.S.,Zarantonello, A.,Harwood, S.L.,Jensen, K.T.,Kjoge, K.,Thogersen, I.B.,Schauser, L.,Karlsen, J.L.,Andersen, G.R.,Enghild, J.J. Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family. Nat Commun, 13:3033-3033, 2022 Cited by PubMed: 35641520DOI: 10.1038/s41467-022-30758-x PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.88 Å) |
Structure validation
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