5OYG
 
 | | Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution | | Descriptor: | Anoctamin-1 | | Authors: | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | | Deposit date: | 2017-09-08 | | Release date: | 2017-12-20 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.06 Å) | | Cite: | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
|
|
5HEJ
 | |
5HEW
 | | Pentameric ligand-gated ion channel ELIC mutant T28D | | Descriptor: | Gamma-aminobutyric-acid receptor subunit beta-1 | | Authors: | Engeler, S, Dutzler, R. | | Deposit date: | 2016-01-06 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels.
Plos Biol., 14, 2016
|
|
5HEO
 | |
5HEU
 | |
5HEH
 | |
2HT3
 | | Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
|
|
2HT4
 | | Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
|
|
2HTL
 | | Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
|
|
2HTK
 | | Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-26 | | Release date: | 2006-09-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
|
|
2J9L
 | | Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5, CHLORIDE ION | | Authors: | Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R. | | Deposit date: | 2006-11-13 | | Release date: | 2007-01-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
Nat.Struct.Mol.Biol., 14, 2006
|
|
2JA3
 | | Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5 | | Authors: | Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R. | | Deposit date: | 2006-11-21 | | Release date: | 2007-01-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5
Nat.Struct.Mol.Biol., 14, 2006
|
|
2EXW
 | |
2EXY
 | |
2EZ0
 | |
2HT2
 | | Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab fragment, heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-25 | | Release date: | 2006-09-19 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
|
|
2HLF
 | | Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex | | Descriptor: | BROMIDE ION, Fab Fragment, Heavy chain, ... | | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | | Deposit date: | 2006-07-07 | | Release date: | 2006-09-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger
J.Mol.Biol., 362, 2006
|
|
7P16
 | |
7P14
 | | Structure of full-length rXKR9 in complex with a sybody at 3.66A | | Descriptor: | DIUNDECYL PHOSPHATIDYL CHOLINE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sybody, ... | | Authors: | Straub, M.S, Sawicka, M, Dutzler, R. | | Deposit date: | 2021-07-01 | | Release date: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Cryo-EM structures of the caspase activated protein XKR9 involved in apoptotic lipid scrambling.
Elife, 10, 2021
|
|
7P5M
 | | Cryo-EM structure of human TTYH2 in lipid nanodiscs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 2 | | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | | Deposit date: | 2021-07-14 | | Release date: | 2021-08-11 | | Last modified: | 2021-09-08 | | Method: | ELECTRON MICROSCOPY (3.92 Å) | | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.
Nat Commun, 12, 2021
|
|
7P5C
 | | Cryo-EM structure of human TTYH3 in Ca2+ and GDN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 3 | | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | | Deposit date: | 2021-07-14 | | Release date: | 2021-08-11 | | Last modified: | 2021-09-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.
Nat Commun, 12, 2021
|
|
7P54
 | | Cryo-EM structure of human TTYH2 in GDN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 2 | | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | | Deposit date: | 2021-07-14 | | Release date: | 2021-08-11 | | Last modified: | 2021-09-08 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.
Nat Commun, 12, 2021
|
|
7P5J
 | | Cryo-EM structure of human TTYH1 in GDN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 1 | | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | | Deposit date: | 2021-07-14 | | Release date: | 2021-08-11 | | Last modified: | 2021-09-08 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.
Nat Commun, 12, 2021
|
|
6QMB
 | | Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (closed state) | | Descriptor: | CALCIUM ION, Predicted protein | | Authors: | Kalienkova, V, Clerico Mosina, V, Bryner, L, Oostergetel, G.T, Dutzler, R, Paulino, C. | | Deposit date: | 2019-02-01 | | Release date: | 2019-03-06 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM.
Elife, 8, 2019
|
|
6QPB
 | | Cryo-EM structure of calcium-free mTMEM16F lipid scramblase in digitonin | | Descriptor: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6 | | Authors: | Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C. | | Deposit date: | 2019-02-13 | | Release date: | 2019-03-06 | | Last modified: | 2019-03-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.
Elife, 8, 2019
|
|
