2HLF

Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex

Summary for 2HLF

• Entry DOI: 10.2210/pdb2hlf/pdb
• Related: 1OTS
• Descriptor: H(+)/Cl(-) exchange transporter clcA, Fab Fragment, Heavy chain, Fab Fragment, Light chain, ... (4 entities in total)
• Functional Keywords: clc family of channels and transpoters, h+/cl- antiporter, membrane protein, fab complex, proton transport
• Biological source: Escherichia coli; More
• Cellular location: Cell inner membrane; Multi-pass membrane protein (Probable): P37019
• Total number of polymer chains: 6
• Total formula weight: 188372.47

Authors

Accardi, A.,Lobet, S.,Williams, C.,Miller, C.,Dutzler, R. (deposition date: 2006-07-07, release date: 2006-09-19, Last modification date: 2023-08-30)

• Primary citation: Accardi, A.,Lobet, S.,Williams, C.,Miller, C.,Dutzler, R.; Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger; J.Mol.Biol., 362:691-699, 2006; PubMed: 16949616; DOI: 10.1016/j.jmb.2006.07.081

Experimental method

X-RAY DIFFRACTION (3.3 Å)