2HT2

Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex

Summary for 2HT2

• Entry DOI: 10.2210/pdb2ht2/pdb
• Related: 1OTS 2HLF 2HT3 2HT4 2HTK 2HTL
• Descriptor: H(+)/Cl(-) exchange transporter clcA, Fab fragment, heavy chain, Fab fragment, light chain, ... (4 entities in total)
• Functional Keywords: clc family of channel and transporters, h+/cl- antiporter, membrane protein, fab complex
• Biological source: Escherichia coli; More
• Cellular location: Cell inner membrane; Multi-pass membrane protein (Probable): P37019
• Total number of polymer chains: 6
• Total formula weight: 194455.28

Authors

Accardi, A.,Lobet, S.,Williams, C.,Miller, C.,Dutzler, R. (deposition date: 2006-07-25, release date: 2006-09-19, Last modification date: 2021-10-20)

• Primary citation: Accardi, A.,Lobet, S.,Williams, C.,Miller, C.,Dutzler, R.; Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.; J.Mol.Biol., 362:691-699, 2006; PubMed: 16949616; DOI: 10.1016/j.jmb.2006.07.081

Experimental method

X-RAY DIFFRACTION (3.32 Å)