2EZ0

Crystal structure of the S107A/E148Q/Y445A mutant of EcClC, in complex with a FaB fragment

Summary for 2EZ0

• Entry DOI: 10.2210/pdb2ez0/pdb
• Related: 1OTS 2exw 2exy
• Descriptor: H(+)/Cl(-) exchange transporter clcA, Fab Fragment (Heavy Chain), Fab Fragment (Light Chain), ... (4 entities in total)
• Functional Keywords: clc family of channels and transporters, h+/cl- antiporter, membrane protein-fab complex, membrane protein
• Biological source: Escherichia coli; More
• Cellular location: Cell inner membrane; Multi-pass membrane protein (Probable): P37019
• Total number of polymer chains: 6
• Total formula weight: 194545.40

Authors

Lobet, S.,Dutzler, R. (deposition date: 2005-11-10, release date: 2006-01-24, Last modification date: 2023-08-23)

• Primary citation: Lobet, S.,Dutzler, R.; Ion-binding properties of the ClC chloride selectivity filter.; Embo J., 25:24-33, 2006; PubMed: 16341087; DOI: 10.1038/sj.emboj.7600909

Experimental method

X-RAY DIFFRACTION (3.54 Å)