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4UI2

Crystal structure of the ternary RGMB-BMP2-NEO1 complex

Summary for 4UI2
Entry DOI10.2210/pdb4ui2/pdb
Related4UHY 4UHZ 4UI0 4UI1
DescriptorNEOGENIN, BONE MORPHOGENETIC PROTEIN 2, BMP2, REPULSIVE GUIDANCE MOLECULE C, RGMC, HEMOJUVELIN, ... (7 entities in total)
Functional Keywordsrepulsive guidance molecule, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling, neogenin, signaling protein
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains4
Total formula weight84505.59
Authors
Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. (deposition date: 2015-03-27, release date: 2015-05-06, Last modification date: 2020-07-29)
Primary citationHealey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C.
Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
Nat.Struct.Mol.Biol., 22:458-, 2015
Cited by
PubMed: 25938661
DOI: 10.1038/NSMB.3016
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.15 Å)
Structure validation

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