4UHY

Crystal structure of the human RGMA-BMP2 complex

Summary for 4UHY

Entry DOI	10.2210/pdb4uhy/pdb
Related	4UHZ 4UI0 4UI1 4UI2
Descriptor	BONE MORPHOGENETIC PROTEIN 2, REPULSIVE GUIDANCE MOLECULE A (2 entities in total)
Functional Keywords	signaling protein, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted: P12643 Cell membrane ; Lipid-anchor, GPI-anchor : Q96B86
Total number of polymer chains	3
Total formula weight	37476.54
Authors	Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. (deposition date: 2015-03-27, release date: 2015-05-06, Last modification date: 2015-06-17)
Primary citation	Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein. Nat.Struct.Mol.Biol., 22:458-, 2015 Cited by PubMed: 25938661 DOI: 10.1038/NSMB.3016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation