4UI1

Crystal structure of the human RGMC-BMP2 complex

Summary for 4UI1

Entry DOI	10.2210/pdb4ui1/pdb
Related	4UHY 4UHZ 4UI0 4UI2
Descriptor	BONE MORPHOGENETIC PROTEIN 2, HEMOJUVELIN, NITRATE ION, ... (6 entities in total)
Functional Keywords	signaling protein, bone morphogenetic protein pathway, hemojuvelin, morphogen, axon guidance, cell surface receptor signaling
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted: P12643 Cell membrane ; Lipid-anchor, GPI-anchor : Q6ZVN8
Total number of polymer chains	4
Total formula weight	51340.89
Authors	Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. (deposition date: 2015-03-27, release date: 2015-05-06, Last modification date: 2015-06-17)
Primary citation	Healey, E.G.,Bishop, B.,Elegheert, J.,Bell, C.H.,Padilla-Parra, S.,Siebold, C. Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein. Nat.Struct.Mol.Biol., 22:458-, 2015 Cited by PubMed: 25938661 DOI: 10.1038/NSMB.3016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation