4HMH
Crystal structure of tankyrase 2 in complex with 7,3-dihydroxyflavone
Summary for 4HMH
Entry DOI | 10.2210/pdb4hmh/pdb |
Related | 3U9H 3U9Y 3UA9 4HKI 4HKK 4HKN 4HL5 4HLF 4HLG 4HLH 4HLK 4HLM |
Descriptor | Tankyrase-2, ZINC ION, SULFATE ION, ... (8 entities in total) |
Functional Keywords | protein-ligand complex, diphtheria toxin like fold, transferase, adp-ribosylation |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q9H2K2 Q9H2K2 |
Total number of polymer chains | 2 |
Total formula weight | 28027.75 |
Authors | Narwal, M.,Haikarainen, T.,Lehtio, L. (deposition date: 2012-10-18, release date: 2012-10-31, Last modification date: 2023-09-20) |
Primary citation | Narwal, M.,Haikarainen, T.,Fallarero, A.,Vuorela, P.M.,Lehtio, L. Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56:3507-3517, 2013 Cited by PubMed: 23574272DOI: 10.1021/jm3018783 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report