Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4HLF

Crystal structure of Tankyrase 2 in complex with 7,3',4'-Trihydroxyflavone

Summary for 4HLF
Entry DOI10.2210/pdb4hlf/pdb
Related3U9H 3U9Y 3UA9 4HKI 4HKK 4HKN 4HL5 4HLG 4HLH 4HLK 4HLM 4HMH
DescriptorTankyrase-2, ZINC ION, SULFATE ION, ... (8 entities in total)
Functional Keywordsprotein-ligand complex, diphtheria toxin like fold, transferase, adp-ribosylation
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: Q9H2K2 Q9H2K2
Total number of polymer chains4
Total formula weight56087.49
Authors
Narwal, M.,Haikarainen, T.,Lehtio, L. (deposition date: 2012-10-17, release date: 2012-10-31, Last modification date: 2023-09-20)
Primary citationNarwal, M.,Haikarainen, T.,Fallarero, A.,Vuorela, P.M.,Lehtio, L.
Screening and structural analysis of flavones inhibiting tankyrases.
J.Med.Chem., 56:3507-3517, 2013
Cited by
PubMed: 23574272
DOI: 10.1021/jm3018783
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon