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4HLK

Crystal structure of Tankyrase 2 in complex with 4'-methylflavone

Summary for 4HLK
Entry DOI10.2210/pdb4hlk/pdb
Related3U9H 3U9Y 3UA9 4HKI 4HKK 4HKN 4HL5 4HLF 4HLG 4HLH 4HLM 4HMH
DescriptorTankyrase-2, SULFATE ION, 2-(4-methylphenyl)-4H-chromen-4-one, ... (8 entities in total)
Functional Keywordsprotein-ligand complex, diphtheria toxin like fold, transferase, adp-ribosylation
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight55821.34
Authors
Narwal, M.,Haikarainen, T.,Lehtio, L. (deposition date: 2012-10-17, release date: 2012-10-31, Last modification date: 2023-09-20)
Primary citationNarwal, M.,Haikarainen, T.,Fallarero, A.,Vuorela, P.M.,Lehtio, L.
Screening and structural analysis of flavones inhibiting tankyrases.
J.Med.Chem., 56:3507-3517, 2013
Cited by
PubMed: 23574272
DOI: 10.1021/jm3018783
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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