4B8L

Aurora B kinase P353G mutant

Summary for 4B8L

• Entry DOI: 10.2210/pdb4b8l/pdb
• Related: 2BFX 2BFY 2VGO 2VGP 2VRX 3ZTX 4B8M
• Descriptor: AURORA KINASE B-A, INNER CENTROMERE PROTEIN A, 9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-9H-purin-6-amine (3 entities in total)
• Functional Keywords: cell cycle, cancer
• Biological source: XENOPUS LAEVIS (AFRICAN CLAWED FROG); More
• Cellular location: Nucleus: Q6DE08; Chromosome, centromere: O13024
• Total number of polymer chains: 2
• Total formula weight: 39183.94

Authors

Sessa, F.,Villa, F. (deposition date: 2012-08-28, release date: 2013-07-10)

• Primary citation: Sessa, F.,Villa, F.; Structural and Biochemical Analysis of an Aurora B Kinase Mutant Reveals a Multistep Activation Mechanism; To be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)