3OVE
Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide
Summary for 3OVE
Entry DOI | 10.2210/pdb3ove/pdb |
Related | 2H5K 3IMD 3IMJ 3IN7 3IN8 3KFJ 3OV1 3S8L 3S8N 3S8O |
Descriptor | Growth factor receptor-bound protein 2, PYAC7CN, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | grb2 sh2 domain, phosphotyrosine binding, signaling protein-antagonist complex, signaling protein/antagonist |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P62993 |
Total number of polymer chains | 2 |
Total formula weight | 14203.23 |
Authors | Clements, J.H.,Martin, S.F. (deposition date: 2010-09-16, release date: 2011-11-02, Last modification date: 2023-12-06) |
Primary citation | Myslinski, J.M.,Delorbe, J.E.,Clements, J.H.,Martin, S.F. Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133:18518-18521, 2011 Cited by PubMed: 22007755DOI: 10.1021/ja2068752 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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