3L27
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant
Summary for 3L27
Entry DOI | 10.2210/pdb3l27/pdb |
Related | 3FKE 3L25 3L26 3L28 3L29 3L2A |
Descriptor | Polymerase cofactor VP35, CHLORIDE ION, PHOSPHATE ION, ... (7 entities in total) |
Functional Keywords | rna binding domain, interferon antiviral evasion, rna replication, rna-binding protein, transcription, host cytoplasm, interferon antiviral system evasion, rna-binding, virion, rna binding protein |
Biological source | Zaire ebolavirus (ZEBOV) |
Cellular location | Virion: Q05127 |
Total number of polymer chains | 4 |
Total formula weight | 58587.22 |
Authors | Leung, D.W.,Prins, K.C.,Borek, D.M.,Farahbakhsh, M.,Tufariello, J.M.,Ramanan, P.,Nix, J.C.,Helgeson, L.A.,Otwinowski, Z.,Honzatko, R.B.,Basler, C.F.,Amarasinghe, G.K. (deposition date: 2009-12-14, release date: 2010-01-26, Last modification date: 2023-09-06) |
Primary citation | Leung, D.W.,Prins, K.C.,Borek, D.M.,Farahbakhsh, M.,Tufariello, J.M.,Ramanan, P.,Nix, J.C.,Helgeson, L.A.,Otwinowski, Z.,Honzatko, R.B.,Basler, C.F.,Amarasinghe, G.K. Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17:165-172, 2010 Cited by PubMed: 20081868DOI: 10.1038/nsmb.1765 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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