3FKE

Structure of the Ebola VP35 Interferon Inhibitory Domain

Summary for 3FKE

Entry DOI	10.2210/pdb3fke/pdb
Descriptor	Polymerase cofactor VP35 (2 entities in total)
Functional Keywords	rna binding domain, coiled coil, interferon antiviral system evasion, rna replication, rna-binding, transcription, rna binding protein
Biological source	Zaire ebolavirus - Mayinga (Zaire, 1976) (ZEBOV)
Cellular location	Virion: Q05127
Total number of polymer chains	2
Total formula weight	28421.05
Authors	Amarasinghe, G.K.,Leung, D.W.,Ginder, N.D.,Honzatko, R.B.,Nix, J.,Basler, C.F.,Fulton, D.B. (deposition date: 2008-12-16, release date: 2009-01-13, Last modification date: 2024-02-21)
Primary citation	Leung, D.W.,Ginder, N.D.,Fulton, D.B.,Nix, J.,Basler, C.F.,Honzatko, R.B.,Amarasinghe, G.K. Structure of the Ebola VP35 interferon inhibitory domain. Proc.Natl.Acad.Sci.USA, 106:411-416, 2009 Cited by PubMed: 19122151 DOI: 10.1073/pnas.0807854106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation