2YDM

Structural characterization of angiotensin-I converting enzyme in complex with a selenium analogue of captopril

Summary for 2YDM

• Entry DOI: 10.2210/pdb2ydm/pdb
• Related: 1O86 1O8A 1UZE 1UZF 2C6F 2C6N 2IUL 2IUX 2XY9 2XYD
• Descriptor: ANGIOTENSIN CONVERTING ENZYME, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total)
• Functional Keywords: hydrolase, antihypertensive agents
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Angiotensin-converting enzyme, soluble form: Secreted. Cell membrane; Single-pass type I membrane protein: P12821
• Total number of polymer chains: 1
• Total formula weight: 69306.16

Authors

Akif, M.,Masuyer, G.,Schwager, S.L.U.,Bhuyan, B.J.,Mugesh, G.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2011-03-22, release date: 2011-09-14, Last modification date: 2023-12-20)

• Primary citation: Akif, M.,Masuyer, G.,Schwager, S.L.U.,Bhuyan, B.J.,Mugesh, G.,Isaac, R.E.,Sturrock, E.D.,Acharya, K.R.; Structural Characterization of Angiotensin-I Converting Enzyme in Complex with a Selenium Analogue of Captopril; FEBS J., 278:3644-, 2011; PubMed: 21810173; DOI: 10.1111/J.1742-4658.2011.08276.X

Experimental method

X-RAY DIFFRACTION (2.44 Å)