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2C6N

Structure of human somatic angiontensin-I converting enzyme N domain with lisinopril

Summary for 2C6N
Entry DOI10.2210/pdb2c6n/pdb
Related2C6F
Related PRD IDPRD_000560
DescriptorANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywordshydrolase, angiotensin-i converting enzyme, n domain, zinc metallopeptidase, metalloprotease, angiotensin, lisinopril, carboxypeptidase, glycoprotein, metal-binding, phosphorylation, protease, transmembrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total formula weight144061.86
Authors
Corradi, H.R.,Schwager, S.L.U.,Nichinda, A.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2005-11-10, release date: 2006-03-15, Last modification date: 2023-12-13)
Primary citationCorradi, H.R.,Schwager, S.L.,Nchinda, A.T.,Sturrock, E.D.,Acharya, K.R.
Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design.
J. Mol. Biol., 357:964-974, 2006
Cited by
PubMed: 16476442
DOI: 10.1016/j.jmb.2006.01.048
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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