2XYD

human Angiotenisn converting enzyme N-domain in complex with Phosphinic tripeptide

Summary for 2XYD

• Entry DOI: 10.2210/pdb2xyd/pdb
• Related: 1O86 1O8A 1UZE 1UZF 2C6F 2C6N 2IUL 2IUX 2XY9
• Descriptor: ANGIOTENSIN-CONVERTING ENZYME, TETRAETHYLENE GLYCOL, HEXAETHYLENE GLYCOL, ... (12 entities in total)
• Functional Keywords: hydrolase, zinc metallopeptidase
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 146469.40

Authors

Akif, M.,Schwager, S.L.,Anthony, C.S.,Czarny, B.,Beau, F.,Dive, V.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2010-11-17, release date: 2011-05-11, Last modification date: 2023-12-20)

• Primary citation: Akif, M.,Schwager, S.L.,Anthony, C.S.,Czarny, B.,Beau, F.,Dive, V.,Sturrock, E.D.,Acharya, K.R.; Novel Mechanism of Inhibition of Human Angiotensin-I-Converting Enzyme (Ace) by a Highly Specific Phosphinic Tripeptide.; Biochem.J., 436:53-, 2011; PubMed: 21352096; DOI: 10.1042/BJ20102123

Experimental method

X-RAY DIFFRACTION (2.15 Å)