2C6F

Structure of human somatic angiontensin-I converting enzyme N domain

Summary for 2C6F

• Entry DOI: 10.2210/pdb2c6f/pdb
• Related: 2C6N
• Descriptor: ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: hydrolase, angiotensin-i converting enzyme, n domain, zinc metallopeptidase, metalloprotease, angiotensin, lisinopril, alternative splicing, carboxypeptidase, glycoprotein, metal-binding, phosphorylation, protease, transmembrane
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 144438.98

Authors

Corradi, H.R.,Schwager, S.L.U.,Nichinda, A.,Sturrock, E.D.,Acharya, K.R. (deposition date: 2005-11-09, release date: 2006-11-08, Last modification date: 2023-12-13)

• Primary citation: Corradi, H.R.,Schwager, S.L.U.,Nchinda, A.T.,Sturrock, E.D.,Acharya, K.R.; Crystal Structure of the N Domain of Human Somatic Angiotensin I-Converting Enzyme Provides a Structural Basis for Domain-Specific Inhibitor Design.; J.Mol.Biol., 357:964-, 2006; PubMed: 16476442; DOI: 10.1016/J.JMB.2006.01.048

Experimental method

X-RAY DIFFRACTION (3.01 Å)