2PKL

Androgen receptor LBD with small molecule

Summary for 2PKL

• Entry DOI: 10.2210/pdb2pkl/pdb
• Related: 2PIN 2PIO 2PIP 2PIQ 2PIR 2PIT 2PIU 2PIV 2PIW 2PIX
• Descriptor: Androgen receptor, ARA70 peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ... (5 entities in total)
• Functional Keywords: androgen receptor coactivators af2 inhibitors, hormone receptor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P10275
• Total number of polymer chains: 2
• Total formula weight: 30710.40

Authors

Estebanez-Perpina, E.,Arnold, A.A.,Baxter, J.D.,Guy, K.R.,Webb, P.,Fletterick, R.J. (deposition date: 2007-04-17, release date: 2007-09-25, Last modification date: 2024-02-21)

• Primary citation: Estebanez-Perpina, E.,Arnold, L.A.,Arnold, A.A.,Nguyen, P.,Rodrigues, E.D.,Mar, E.,Bateman, R.,Pallai, P.,Shokat, K.M.,Baxter, J.D.,Guy, R.K.,Webb, P.,Fletterick, R.J.; A surface on the androgen receptor that allosterically regulates coactivator binding.; Proc.Natl.Acad.Sci.Usa, 104:16074-16079, 2007; PubMed: 17911242; DOI: 10.1073/pnas.0708036104

Experimental method

X-RAY DIFFRACTION (2.49 Å)