2FPV
Dual binding mode of a novel series of DHODH inhibitors
Summary for 2FPV
| Entry DOI | 10.2210/pdb2fpv/pdb |
| Related | 2BXV 2FPT 2FPY 2FQI |
| Descriptor | Dihydroorotate dehydrogenase, mitochondrial, ACETATE ION, SULFATE ION, ... (7 entities in total) |
| Functional Keywords | protein inhibitor compley, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Cellular location | Mitochondrion inner membrane; Single-pass membrane protein: Q02127 |
| Total number of polymer chains | 1 |
| Total formula weight | 44708.24 |
| Authors | Baumgartner, R.,Leban, J. (deposition date: 2006-01-17, release date: 2007-01-23, Last modification date: 2023-08-30) |
| Primary citation | Baumgartner, R.,Walloschek, M.,Kralik, M.,Gotschlich, A.,Tasler, S.,Mies, J.,Leban, J. Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49:1239-1247, 2006 Cited by PubMed: 16480261DOI: 10.1021/jm0506975 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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