2BXV

Dual binding mode of a novel series of DHODH inhibitors

Summary for 2BXV

Entry DOI	10.2210/pdb2bxv/pdb
Related	1D3G 1D3H
Descriptor	DIHYDROOROTATE DEHYDROGENASE, SULFATE ION, ACETATE ION, ... (7 entities in total)
Functional Keywords	oxidoreductase, dihydroorotate dehydrogenase inhibitor, dual binding mode, virtual high-throughput screening, rheumatoid arthritis oxidoreductase
Biological source	HOMO SAPIENS (Human)
Total number of polymer chains	1
Total formula weight	41033.41
Authors	Baumgartner, R.,Walloschek, M.,Karlik, M.,Gotschlich, A.,Tasler, S.,Mies, J.,Leban, J. (deposition date: 2005-07-27, release date: 2006-08-16, Last modification date: 2023-12-13)
Primary citation	Baumgartner, R.,Walloschek, M.,Kralik, M.,Gotschlich, A.,Tasler, S.,Mies, J.,Leban, J. Dual binding mode of a novel series of DHODH inhibitors. J. Med. Chem., 49:1239-1247, 2006 Cited by PubMed: 16480261 DOI: 10.1021/jm0506975 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation