1RHK
Crystal structure of the complex of caspase-3 with a phenyl-propyl-ketone inhibitor
Summary for 1RHK
Entry DOI | 10.2210/pdb1rhk/pdb |
Related | 1PAU 1RHJ 1RHM 1RHQ 1RHR 1RHU |
Related PRD ID | PRD_000231 |
Descriptor | Caspase-3, acetyl-asp-glu-val-fpr, ... (4 entities in total) |
Functional Keywords | cysteine protease, caspase-3, apopain, cpp32, yama, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P42574 P42574 |
Total number of polymer chains | 3 |
Total formula weight | 29155.15 |
Authors | Becker, J.W.,Rotonda, J.,Soisson, S.M. (deposition date: 2003-11-14, release date: 2004-05-11, Last modification date: 2023-09-20) |
Primary citation | Becker, J.W.,Rotonda, J.,Soisson, S.M.,Aspiotis, R.,Bayly, C.,Francoeur, S.,Gallant, M.,Garcia-Calvo, M.,Giroux, A.,Grimm, E.,Han, Y.,McKay, D.,Nicholson, D.W.,Peterson, E.,Renaud, J.,Roy, S.,Thornberry, N.,Zamboni, R. Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis. J.Med.Chem., 47:2466-2474, 2004 Cited by PubMed: 15115390DOI: 10.1021/jm0305523 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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