1PAU
Crystal structure of the complex of apopain with the tetrapeptide aldehyde inhibitor AC-DEVD-CHO
Summary for 1PAU
| Entry DOI | 10.2210/pdb1pau/pdb |
| Related PRD ID | PRD_000422 |
| Descriptor | APOPAIN, ACE-ASP-GLU-VAL-ASJ, ... (4 entities in total) |
| Functional Keywords | cysteine protease, caspase-3, apopain, cpp32, yama, protease-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm: P42574 P42574 |
| Total number of polymer chains | 3 |
| Total formula weight | 29038.99 |
| Authors | Rotonda, J.,Becker, J.W. (deposition date: 1996-06-06, release date: 1997-07-07, Last modification date: 2023-08-09) |
| Primary citation | Rotonda, J.,Nicholson, D.W.,Fazil, K.M.,Gallant, M.,Gareau, Y.,Labelle, M.,Peterson, E.P.,Rasper, D.M.,Ruel, R.,Vaillancourt, J.P.,Thornberry, N.A.,Becker, J.W. The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis. Nat.Struct.Biol., 3:619-625, 1996 Cited by PubMed: 8673606DOI: 10.1038/nsb0796-619 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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