4EDW
Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | V | Beta-nerve growth factor | polymer | 120 | 13515.4 | 1 | UniProt (P01138) Pfam (PF00243) In PDB | Homo sapiens (human) | Beta-NGF |
2 | L | tanezumab Fab light chain | polymer | 214 | 23621.2 | 1 | Homo sapiens | ||
3 | H | tanezumab Fab heavy chain | polymer | 231 | 24959.7 | 1 | Homo sapiens | ||
4 | H | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 62096.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 62188.4 |