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1LM8
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1lm8
STRUCTURE OF A HIF-1A-PVHL-ELONGINB-ELONGINC COMPLEX
Descriptor:elongin B, elongin C, Von Hippel-Lindau disease tumor suppressor, Hypoxia-inducible factor 1 alpha
Authors:Min, J-H, Yang, H., Ivan, M., Gertler, F., Kaelin JR., W.G., Pavletich, N.P.
Deposit date:2002-04-30
Release date:2002-06-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
Science, 296, 2002
1LQB
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1lqb
CRYSTAL STRUCTURE OF A HYDROXYLATED HIF-1 ALPHA PEPTIDE BOUND TO THE PVHL/ELONGIN-C/ELONGIN-B COMPLEX
Descriptor:HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex
Authors:Hon, W.C., Wilson, M.I., Harlos, K., Claridge, T.D., Schofield, C.J., Pugh, C.W., Maxwell, P.H., Ratcliffe, P.J., Stuart, D.I., Jones, E.Y.
Deposit date:2002-05-09
Release date:2002-07-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
Nature, 417, 2002
3HQR
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3hqr
PHD2:MN:NOG:HIF1-ALPHA SUBSTRATE COMPLEX
Descriptor:Egl nine homolog 1 (E.C.1.14.11.-), Hypoxia-inducible factor 1 alpha
Authors:Chowdhury, R., McDonough, M.A., Schofield, C.J.
Deposit date:2009-06-08
Release date:2009-07-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
Structure, 17, 2009
3HQU
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3hqu
PHD2:FE:UN9:PARTIAL HIF1-ALPHA SUBSTRATE COMPLEX
Descriptor:Egl nine homolog 1 (E.C.1.14.11.-), Hypoxia-inducible factor 1 alpha
Authors:Chowdhury, R., McDonough, M.A., Schofield, C.J.
Deposit date:2009-06-08
Release date:2009-07-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
Structure, 17, 2009
4AJY
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4ajy
VON HIPPEL-LINDAU PROTEIN-ELONGINB-ELONGINC COMPLEX, BOUND TO HIF1- ALPHA PEPTIDE
Descriptor:TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, HYPOXIA-INDUCIBLE FACTOR 1-ALPHA, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
Authors:Van Molle, I., Thomann, A., Buckley, D.L., So, E.C., Lang, S., Crews, C.M., Ciulli, A.
Deposit date:2012-02-21
Release date:2012-11-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface.
Chem.Biol., 19, 2012
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entries available on 2014-09-17
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