1PFT
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N-TERMINAL DOMAIN OF TFIIB, NMR
Descriptor:TFIIB
Authors:Zhu, W., Zeng, Q., Colangelo, C.M., Lewis, L.M., Summers, M.F., Scott, R.A.
Deposit date:1996-03-27
Release date:1996-08-17
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The N-terminal domain of TFIIB from Pyrococcus furiosus forms a zinc ribbon.
Nat.Struct.Biol., 3, 1996
1DL6
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SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN
Descriptor:TRANSCRIPTION FACTOR II B (TFIIB)
Authors:Chen, H.-T., Legault, P., Glushka, J., Omichinski, J.G., Scott, R.A.
Deposit date:1999-12-08
Release date:2000-10-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription.
Protein Sci., 9, 2000
1RLY
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RDC-DERIVED MODELS OF THE ZINC RIBBON DOMAIN OF HUMAN GENERAL TRANSCRIPTION TFIIB (ZINC BOUND STRUCTURES)
Descriptor:Transcription initiation factor IIB
Authors:Ghosh, M., Ikura, M.
Deposit date:2003-11-26
Release date:2004-05-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB.
Biochem.J., 378, 2004
1RO4
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RDC-DERIVED MODELS OF THE ZINC RIBBON DOMAIN OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB (ZINC FREE STRUCTURES)
Descriptor:Transcription initiation factor IIB
Authors:Ghosh, M., Ikura, M.
Deposit date:2003-12-01
Release date:2004-05-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB.
Biochem.J., 378, 2004
3WWL
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CRYSTAL STRUCTURE OF LYSINE BIOSYNTHETIC AMINO ACID CARRIER PROTEIN LYSW FROM THERMUS THERMOPHILUS CONJUGATED WITH ALPHA-AMINOADIPATE
Descriptor:Alpha-aminoadipate carrier protein LysW
Authors:Yoshida, A., Tomita, T., Kuzuyama, T., Nishiyama, M.
Deposit date:2014-06-21
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ-LysW complex from Thermus thermophilus
J.Biol.Chem., 2014
5FMF
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THE P-LOBE OF RNA POLYMERASE II PRE-INITIATION COMPLEX
Descriptor:DNA REPAIR HELICASE RAD25, SSL2 (E.C.3.6.4.12), TRANSCRIPTION ELONGATION FACTOR S-II, DST1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, RNA POLYMERASE II PRE-INITIATION COMPLEX, RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1, RPB5, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2, RPB6, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3, RPB8, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5, RPB10, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4, RPB12, RNA POLYMERASE II PRE-INITIATION COMPLEX, TOA1, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2, TOA2, TRANSCRIPTION INITIATION FACTOR IIB, SUA7, TATA-BOX-BINDING PROTEIN, TBP, TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT ALPHA, TFA1, TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA, TFA2, RNA POLYMERASE II PRE-INITIATION COMPLEX, TFG1, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT BETA, TFG2 (E.C.3.6.4.12), RNA POLYMERASE II TRANSCRIPTION FACTOR B SUBUNIT 2, TFB2, RNA POLYMERASE II TRANSCRIPTION FACTOR B SUBUNIT 5, TFB5, DNA REPAIR HELICASE RAD3 (E.C.3.6.4.12)
Authors:Murakami, K., Tsai, K., Kalisman, N., Bushnell, D.A., Asturias, F.J., Kornberg, R.D.
Deposit date:2015-11-03
Release date:2015-11-25
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of an RNA Polymerase II Pre-Initiation Complex
Proc.Natl.Acad.Sci.USA, 112, 2015
5FYW
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TRANSCRIPTION INITIATION COMPLEX STRUCTURES ELUCIDATE DNA OPENING (OC)
Descriptor:DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, TRANSCRIPTION INITIATION FACTOR IIB, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT ALPHA, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT BETA (E.C.3.6.4.12), TRANSCRIPTION INITIATION FACTOR IIA LARGE SUBUNIT, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2, TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT ALPHA, TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA
Authors:Plaschka, C., Hantsche, M., Dienemann, C., Burzinski, C., Plitzko, J., Cramer, P.
Deposit date:2016-03-10
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
5FZ5
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TRANSCRIPTION INITIATION COMPLEX STRUCTURES ELUCIDATE DNA OPENING (CC)
Descriptor:DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, TRANSCRIPTION INITIATION FACTOR IIB, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT ALPHA, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT BETA (E.C.3.6.4.12), TRANSCRIPTION INITIATION FACTOR IIA LARGE SUBUNIT, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2, TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT ALPHA, TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA
Authors:Plaschka, C., Hantsche, M., Dienemann, C., Burzinski, C., Plitzko, J., Cramer, P.
Deposit date:2016-03-10
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Transcription Initiation Complex Structures Elucidate DNA Opening
Nature, 533, 2016
5IY6
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HUMAN HOLO-PIC IN THE CLOSED STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IY7
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HUMAN HOLO-PIC IN THE OPEN STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit RPB5, DNA-directed RNA polymerase II subunit RPB6, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit RPB8, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB12, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor TFIIS, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IY8
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HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IY9
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HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IYA
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HUMAN CORE-PIC IN THE CLOSED STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IYB
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HUMAN CORE-PIC IN THE OPEN STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IYC
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HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
5IYD
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HUMAN CORE-PIC IN THE INITIAL TRANSCRIBING STATE (NO IIS)
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-05-25
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening
Nature, 533, 2016
1VD4
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SOLUTION STRUCTURE OF THE ZINC FINGER DOMAIN OF TFIIE ALPHA
Descriptor:Transcription initiation factor IIE, alpha subunit
Authors:Okuda, M., Tanaka, A., Arai, Y., Satoh, M., Okamura, H., Nagadoi, A., Hanaoka, F., Ohkuma, Y., Nishimura, Y.
Deposit date:2004-03-18
Release date:2004-10-05
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.
J.Biol.Chem., 279, 2004
3K1F
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CRYSTAL STRUCTURE OF RNA POLYMERASE II IN COMPLEX WITH TFIIB
Descriptor:DNA-directed RNA polymerase II subunit RPB1 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB2 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB3 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB4 (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III subunit RPABC1 (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III subunit RPABC2 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB7 (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III subunit RPABC3 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB9 (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III subunit RPABC5 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB11 (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III subunit RPABC4 (E.C.2.7.7.6), Transcription initiation factor IIB
Authors:Kostrewa, D., Zeller, M.E., Armache, K.-J., Seizl, M., Leike, K., Thomm, M., Cramer, P.
Deposit date:2009-09-27
Release date:2009-11-10
Modification date:2013-05-01
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:RNA polymerase II-TFIIB structure and mechanism of transcription initiation.
Nature, 462, 2009
3K7A
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CRYSTAL STRUCTURE OF AN RNA POLYMERASE II-TFIIB COMPLEX
Descriptor:DNA-directed RNA polymerase II subunit RPB1 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB2 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB
Authors:Liu, X., Bushnell, D.A., Wang, D., Calero, G., Kornberg, R.D.
Deposit date:2009-10-12
Release date:2009-11-24
Modification date:2012-09-05
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
Science, 327, 2010
4BBR
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STRUCTURE OF RNA POLYMERASE II-TFIIB COMPLEX
Descriptor:DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, TRANSCRIPTION INITIATION FACTOR IIB
Authors:Sainsbury, S., Niesser, J., Cramer, P.
Deposit date:2012-09-27
Release date:2012-11-14
Modification date:2013-01-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex
Nature, 493, 2013
4BBS
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STRUCTURE OF AN INITIALLY TRANSCRIBING RNA POLYMERASE II-TFIIB COMPLEX
Descriptor:DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, TRANSCRIPTION INITIATION FACTOR IIB
Authors:Sainsbury, S., Niesser, J., Cramer, P.
Deposit date:2012-09-27
Release date:2012-11-14
Modification date:2013-01-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure and Function of the Initially Transcribing RNA Polymerase II-TFIIB Complex
Nature, 493, 2013
4V1N
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ARCHITECTURE OF THE RNA POLYMERASE II-MEDIATOR CORE TRANSCRIPTION INITIATION COMPLEX
Descriptor:DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, TRANSCRIPTION INITIATION FACTOR IIB, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT ALPHA, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT BETA (E.C.3.6.4.12)
Authors:Plaschka, C., Lariviere, L., Wenzeck, L., Hemann, M., Tegunov, D., Petrotchenko, E.V., Borchers, C.H., Baumeister, W., Herzog, F., Villa, E., Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Modification date:2015-09-16
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4V1O
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Molmil generated image of 4v1o
ARCHITECTURE OF THE RNA POLYMERASE II-MEDIATOR CORE TRANSCRIPTION INITIATION COMPLEX
Descriptor:DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4, TRANSCRIPTION INITIATION FACTOR IIB, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT ALPHA, TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT BETA (E.C.3.6.4.12), MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6, MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8, MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20, MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11, MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18, MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22
Authors:Plaschka, C., Lariviere, L., Wenzeck, L., Hemann, M., Tegunov, D., Petrotchenko, E.V., Borchers, C.H., Baumeister, W., Herzog, F., Villa, E., Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Modification date:2015-09-16
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
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